Evaluation of the Value of MRI Combined with DWI Imaging in Patients with Ischemic Penumbra in Early Cerebral Infarction
Objective Explore the clinical value of MRI combined DWI in evaluating ischemic penumbra patients with early Cl.Methods In this study,100 patients with early cerebral infarction in our hospital from January 2021 to December 2022 were selected as the study subjects.According to the onset time,they were divided into a hyperacute phase group of 44 patients(onset＜6 hours)and an acute phase group of 56 patients(onset 6-12 hours).All patients underwent MRI combined with DWI,to measure relevant parameter data map obtained by MRI combined with DWI was automatically generated.The relative values of various parameters in the ischemic penumbra at different times were obtained,namely,rDCavg,rADC,and rFA.Compare the quantitative parameters of the affected side and the healthy side in patients with early cerebral infarction;compare the quantitative parameters of ischemic penumbra between the hyperacute phase group and the acute phase group;the predictive value of quantitative parameters for ischemic penumbra was analyzed using ROC curves.Results The levels of DCavg,ADC,and FA in the infarcted core and ischemic penumbra lower than contralateral area(P＜0.05);the levels of DCavg,ADC,and FA in the infarcted core lower than ischemic penumbra(P＜0.05).RDCavg,rADC,and rFA in the hyperacute group were higher than those in the acute group(P＜0.05).The ROC curve analysis showed that among the predictive values of ischemic penumbra,the sensitivity and specificity of DCavg were 81.0％and 87.0％,respectively;ADC has a sensitivity of 65.0％and a specificity of 63.0％;the sensitivity and specificity of FA were 65.0％and 63.0％,respectively;the sensitivity and specificity of combined prediction were 88.5％and 96.0％,respectively.The sensitivity and specificity of combined prediction were higher than those of DAavg,ADC,and FA(P＜0.05).Conclusion MRI combined with DWI imaging has good value in evaluating patients with ischemic penumbra in early cerebral infarction,and can improve the predictive sensitivity and specificity.
Magnetic Resonance imagingDiffusion Weighted imagingEarly Cerebral Infarctionischemic Penumbra
万方数据
维普
