Objective To explore the diagnostic value of functional magnetic resonance imaging(fMRI)in viral encephalitis(VE)and intracranial tuberculosis(IT).Methods Forty-eight patients with VE,41 patients with IT,50 patients with subacute cerebral infarction and 50 patients with low-grade glioma admitted to our hospital from January 2021 to December 2022 were included in the study.All patients underwent conventional MRI,three-dimensional arterial spin labeling(3D-ASL),diffusion-weighted imaging(DWI)and hydrogen proton MR Spectroscopy(1H-MRS)imaging.The ADC values,rCBF values and 1H-MRS results of VE,IT,subacute cerebral infarction and low-grade glioma groups were observed and compared.Results The mean ADC values in IT patients were higher than those in the normal control area,while the mean ADC values in VE patients,subacute cerebral infarction and low-grade glioma patients were lower than those in the normal control area.rADC in IT patients was higher than that in VE patients,subacute cerebral infarction patients and low-grade glioma patients,and the most significant difference was found in VE patients and subacute cerebral infarction patients(P＜0.05).The average rCBF of patients with low-grade glioma was higher than that of the normal control area,while the average rCBF of patients with IT and subacute cerebral infarction was lowerthan that of the normal control area,and the average rCBF of patients with subacute cerebral infarction was the most obvious reduction,while the average rCBF of patients with VE was slightly lower than that of the normal control area.The rrCBF of low-grade glioma patients was higher than that of VE patients,IT patients and subacute cerebral infarction patients,and the subacute cerebral infarction patients were the most significant(P＜0.05).The Cho/Cr and Cho/NAA ratios in low-grade glioma patients were significantly higher than those in VE patients,IT patients and subacute cerebral infarction patients(P＜0.05).The Cho/Cr and Cho/NAA ratios in VE patients were lowerthan those in IT patients(P＜0.05).Conclusion ADC value,rCBF value,Cho/Cr and Cho/NAA ratio can provide important information for the diagnosis and differential diagnosis of VE and IT,which is helpful for the judgment of treatment plan and prognosis.
Functional Magnetic ResonanceViral EncephalitisIntracranial TuberculosisDiagnostic Value
万方数据
维普
