Objective To investigate the value of ECG-gated dual-source computed tomography angiography(DSCTA)in the diagnosis of single atrium(SV)and single atrium(SA).Methods DSCTA was performed in 27 patients with severe complex congenital heart with disease SV combined SA.The classification diagnosis was made,and the complicated deformities were summarized.Results According to the morphological characteristics of the main ventricular cavity,the 27 patients were classified as left ventricular type(8 cases),right ventricular type(12 cases)and uncertain type(7 cases)(29.63%,44.44%and 26.00%,respectively).Atrial situs solitus was found in 9(9/27,33.33%),atrial situs inversus was found in 1(1/27,3.70%)and atrial situs ambiguous was found in 17(17/27,62.96%,including right atrial isomerism in 16 and left atrial isomerism in 1 patient).The patients complicated with 30 kinds,totally 188 deformities.There were statistically significant differences between the left ventricular double outlet,right ventricular double outlet and trabecular capsule of three types of single ventricle(P<0.05).There were statistical differences in right atrial isomerism between uncertainty type and left ventricular type single ventricle(P<0.05),and no statistically significant differences in other aspects(P>0.05).Left pulmonary artery diameter,abdominal aorta diameter and McGoon index measured by two methods of DSCT and TTE were correlated.Conclusion DSCTA can accurately diagnose single ventricle,single atrium and associated malformations,and provide reference for surgical indications and risk assessment.