首页|心脏磁共振评估非梗阻冠状动脉心肌梗死预后的研究

心脏磁共振评估非梗阻冠状动脉心肌梗死预后的研究

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目的 探讨心血管磁共振(CMR)对冠状动脉非梗阻心肌梗死(MINOCA)患者预后的评价价值.方法 对388名接受心脏磁共振(CMR)评估的MINOCA患者进行分析,并对其主要临床终点进行前瞻性追踪.结果 74%的心肌炎、心肌梗死和心肌病患者CMR能够确定肌钙蛋白升高的原因,而正常CMR的确诊率为26%.5.7%的患者死亡,心肌病组预后最差(病死率15%,P<0.001),心肌炎组和正常心肌病组的病死率分别为4%和2%.在多变量COX回归模型中(包括临床和CMR参数),心肌病的CMR诊断和心电图ST段抬高仍然是唯一两个有意义的死亡率预测因素.以心电图ST段抬高和心肌梗死诊断为危险指标,0、1和2个因素的死亡风险率分别为2%、11%和21%(P<0.0001).结论 MINOCA患者中,CMR(发病后37天的中位数)在74%的患者中确定了最终诊断.心肌病病死率最高,其次是心肌梗塞.死亡率的最强预测因素是心肌病的CMR诊断和心电图ST段抬高.
A Study on the Prognosis of Nonobstructive Coronary Artery Myocardial Infarction Evaluated by Cardiac Magnetic Resonance Imaging
Objective To explore the impact of cardiovascular magnetic resonance(CMR)on the prognosis of patients with non obstructive myocardial infarction(MINOCA)in coronary arteries.Methods An analysis was conducted on 388 MINOCA patients who underwent cardiac magnetic resonance(CMR)evaluation,and their primary clinical endpoints were prospectively tracked.Results Among 74%of patients(myocarditis,myocardial infarction,and cardiomyopathy),CMR(median 37 days)was able to determine the cause of elevated troponin,while the diagnostic rate of normal CMR was 26%.On average follow-up of 1262 days(3.5 years),5.7%of patients died.The prognosis of the cardiomyopathy group was the worst(mortality rate of 15%;pairwise test:19.9;P<0.001),while the mortality rates of the myocarditis group and the normal cardiomyopathy group were 4%and 2%,respectively.In multivariate COX regression models(including clinical and CMR parameters),CMR diagnosis of cardiomyopathy and ST segment elevation on electrocardiogram remain the only two meaningful predictors of mortality.Using electrocardiogram ST segment elevation and myocardial infarction diagnosis as risk indicators,the mortality risk rates for 0,1,and 2 factors were 2%,11%,and 21%,respectively(P<0.001).Conclusion Among MINOCA patients,CMR(median 37 days after onset)was determined as the final diagnosis in 74%of patients.The mortality rate of cardiomyopathy is the highest,followed by myocardial infarction.The strongest predictors of mortality are CMR diagnosis of cardiomyopathy and ST segment elevation on electrocardiogram.

Cardiovascular Magnetic Resonance ImagingCoronary Nonobstructive Myocardial InfarctionMyocarditis

李先江、刘景梅、郭拥军、吕德勇

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东营市人民医院(山东省立医院集团东营医院)医学影像科(山东 东营 257000)

东营市人民医院(山东省立医院集团东营医院)检验科(山东 东营 257000)

东营市利津县盐窝镇中心卫生院放射科(山东 东营 257400)

心血管磁共振 冠状动脉非梗阻心肌梗死 心肌炎

山东省医药卫生科技发展计划项目

202109010604

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(6)