Value of 3.0T Conventional MRI Combined with Multiple b-value DWI in the Diagnosis of Prostate Cancer
Objective To explore the value of 3.0T conventional MRI combined with diffusion weighted imaging(DWI)in the diagnosis of prostate cancer.Methods Retrospective analysis was conducted.Patients were divided into prostate cancer group(n=32)and prostate hyperplasia group(n=33)according to puncture or surgical pathological results.All patients underwent 3.0T routine MRI,routine MRI+multiple b-value DWI examination(b-value 1000s·mmr-2,2000s·mm-2 and 3000s·mm-2,respectively).The diagnostic accuracy,specificity and sensitivity of the two tests were calculated and compared.The ADC values of the prostate hyperplasia group and the prostate cancer group in the DWI examination with different b-values were compared,and the difference of DWI signal intensity and contrast of DWI signal intensity of different b-values between the cancer lesion and the contralateral or surrounding normal tissue in the prostate cancer group were compared.The ADC values of cancer foci in DWI examination with different b-values were compared.Results The accuracy,specificity and sensitivity of 3.0T conventional MRI+multi-b-value DWI were significantly higher than those of conventional MRI(P＜0.05).The ADC values in the BPH group were higher than those in the PCA group with different b-value DWI,the difference was statistically significant(P＜0.05).There were significant differences in DWI signal intensity difference and DWI signal intensity contrast between prostate cancer group and the opposite normal tissue with different b-value(P＜0.05).With the increase of B-value,DWI signal intensity difference decreased and DWI contrast increased.ADC values of cancer foci in different b values were significantly different(P＜0.05),and ADC values decreased with the increase of b value.Conclusion The combined application of 3.0T MRI with b-value DWI is helpful for the differential diagnosis of prostate cancer and hyperplasia,and has high clinical value.
Magnetic Resonance ImagingDiffusion-weighted ImagingMultiple b valuesProstate CancerHyperplasia of Prostate
万方数据
维普
