Quantitative Application of Magnetic Resonance Mapping Technique in Early Renal Function Assessment of Patients with Type 2 Diabetes
Objective To investigate the quantitative application value of magnetic resonance mapping technique in early renal function assessment of patients with type 2 diabetes mellitus(T2DM).Methods This is a case-control study.Eighteen patients with mild DN(eGFR＞60mL/min·1.73m2)and 18 patients with moderate DN(eGFR 60-30)were selected from May 2021 to July 2022 according to the 1∶1 pairing principle mL/min·1.73m2),18 patients with severe DN(eGFR＜30mL/min·1.73m2,a total of 54 patients with DN were selected as the study object,and 54 patients with simple type 2 diabetes were selected as the control group during the same period.Comparing T1 and T2 values,the ROC curve model was used to diagnose DN and predict the AUC,sensitivity and specificity of renal function in patients with DN.Results The values of T1 and T2 in DN group were higher than those in T2DM group(P＜0.05).The values of T1 and T2 in severe group were higher than those in mild and moderate groups(P＜0.05).ROC curve analysis showed that the AUC values of T1,T2 and comprehensive parameters were(0.801,0.809,0.840,P＜0.05),and the sensitivity were 66.70％,63.00％,72.20％,The specificity was 85.20％,90.70％and 88.90％.T1,T2 and combined parameters predicted the AUC values of renal function in DN patients(0.782,0.770,0.824,P＜0.05),The sensitivity,respectively.Conclusion Magnetic resonance mapping can quantitatively evaluate renal function in patients with type 2 diabetes,which is helpful for early detection of DN.
Magnetic ResonanceQuantitative Relaxation TimeType 2 Diabetes MellitusDiabetic NephropathyRenal Function
万方数据
维普
