Coronary flow reserve(FFR)is the gold standard for evaluating the physiologic function of the coronary vasculature.Noninvasive flow reserve fraction(CT-FFR)based on coronary CT angiography is a new technique for the study of coronary artery disease,which applies computational fluid dynamics to anatomical data providing clinicians with further functional assessment to guide therapeutic decisions.The potential of CT-FFR is now recognized.In this review,the basic principles of CT-FFR,the diagnostic efficacy of CT-FFR for coronary artery disease and the factors affecting it,limitations and shortcomings,and future directions are presented.
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