冠状动脉周围脂肪CT衰减指数联合CT-FFR对急性冠状动脉综合征患者MACE事件预测价值
Value of Peripheral Coronary Fat CT Attenuation Index Combined with CT-FFR in Predicting MACE Events in Patients with Acute Coronary Syndrome
孙刚 1常艺桐 1徐娜 1孟庆涛 1朱霓2
作者信息
- 1. 安徽医科大学附属滁州医院(滁州市第一人民医院)影像中心(安徽滁州 239000)
- 2. 中国人民解放军第二军医大学(上海 200433)
- 折叠
摘要
目的 探讨分析冠状动脉周围脂肪CT衰减指数(FAI)联合CT-FFR对急性冠状动脉综合征(ACS)患者MACE事件预测价值.方法 选择2020年1月～2022年7月在我院接受PCI手术治疗的ACS患者162例,根据患者术后1年是否发生MACE,将其分为MACE组(37例)和非MACE组(125例).记录两组患者临床资料,并进行FAI及CT-FFR检查,进行多因素Logistic回归分析,并采用ROC曲线分析FAI、CT-FFR对ACS患者PCI术后MACE发生的预测价值.结果 MACE组患者FAI显著高于非MACE组患者(P＜0.05),且MACE组患者CT-FFR显著低于非MACE组(P＜0.05).CT-FFR、FAI、年龄以及血管病变直数进入回归模型(P＜0.05),为影响ACS患者PCI术后MACE发生的独立危险因素.采用ROC曲线分析FAI、CT-FFR对ACS患者PCI术后MACE的预测价值,结果显示,FAI曲线下面积为0.695、CT-FFR曲线下面积为0.771,FAI联合CT-FFR曲线下面积为0.943.结论 冠状动脉周围脂肪CT衰减指数联合CT血流储备分数对冠状动脉综合征患者PCI术后MACE发生具有着良好的预测价值,术前完善相关检查评估,对于高危患者及时采取有效的预防治疗对策,对于改善患者临床预后具有重要意义.
Abstract
Objective To investigate and analyze the value of peripheral coronary fat CT attenuation index combined with CT-FFR in predicting MACE events in patients with acute coronary syndrome.Methods We selected 162 ACS patients who underwent PCI surgery in our hospital from January 2020 to July 2022,and divided them into MACE group(37 cases)and non-MACE group(125 cases)according to whether MACE occurred 1 year after surgery.The clinical data of patients in the two groups were recorded,and FAI and CT-FFR were examined,multifactorial logistic regression analysis was performed,and ROC curves were used to analyse the predictive value of FAI and CT-FFR on the occurrence of MACE after PCI in ACS patients.Results FAI was significantly higher in patients in the MACE group than in those in the non-MACE group(P＜0.05),and CT-FFR was significantly lower in patients in the MACE group than in those in the non-MACE group(P＜0.05).CT-FFR,FAI,age,and the straight number of vascular lesions entered into the regression model(P＜0.05),and were the independent risk factors affecting the occurrence of MACE after PCI in patients with ACS.ROC curve was used to analyse the predictive value of FAI and CT-FFR for MACE after PCI in patients with ACS,and the results showed that the area under the curve of FAI was 0.695,the area under the curve of CT-FFR was 0.771,and the area under the curve of FAI combined with CT-FFR was 0.943.Condusion The CT attenuation index of peripheral coronary fat combined with CT blood flow reserve fraction has a good predictive value for the occurrence of MACE in patients with coronary syndrome after PCI.Improving the relevant examination and evaluation before surgery is of great significance for the timely adoption of effective preventive and therapeutic countermeasures for high-risk patients,and for improving the clinical prognosis of patients.
关键词
冠状动脉周围脂肪CT衰减指数/CT-FFR/急性冠状动脉综合征/MACE/预测Key words
Peripheral Coronary Fat CT Attenuation Index/CT-FFR/Acute Coronary Syndrome/MACE/Forecast引用本文复制引用
基金项目
国家自然科学基金委员会资助项目(91870376)
出版年
2024
NETL
NSTL
万方数据