Study on the Curative Effect of Combined Minimally Invasive Surgery(RFA and TACE)for B/C Stage Hepatocellular Carcinoma Clinical Laboratory
Objective To evaluate the efficacy of radiofrequency ablation(RFA)and hepatic arterial chemoembolization(TACE)in patients with stage B/C hepatocellular carcinoma.Methods 60 patients with stage B/C hepatocellular carcinoma were followed up for 3 years and divided into single TACE group(n=21)and TACE combined RFA group(n=39).Preoperative and postoperative liver function,MRI imaging data,patient survival and recurrence were analyzed,and the total postoperative survival time and recurrence time of patients were compared.Results There were no significant differences in liver function including albumin,total bilirubin,activated partial thrombin time(APTT),aspartate aminotransferase(AST)and alanine aminotransferase(ALT)between the two groups before and after surgery(P＞0.05).The 18-month and 24-month survival rates in the single TACE group were significantly different from those in the combined radiofrequency ablation group(P＜0.05).Compared with the TACE combined RFA group,the three-year survival hazard ratio and recurrence risk ratio in the single TACE group were 2.4382 and 2.985,respectively,with statistical differences(P＜0.05).Conclusion Patients with stage B/C hepatocellular carcinoma treated with TACE combined with RFA have lower recurrence risk,higher survival rate and better prognosis than those treated with TACE alone.
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