Predictive Value of Magnetic Resonance Imaging Multiple Sequences for Microvascular Invasion in Intrahepatic Mass Cholangiocarcinoma
Objective To Explore the predictive value of magnetic resonance imaging(MRI)multiple sequences for microvascular invasion(MVI)in mass type intrahepatic cholangiocarcinoma(IMCC).Methods Retrospective analysis of the clinical data of 80 IMCC patients admitted to our hospital from January 2017 to January 2023,all of whom underwent preoperative MRI multi sequence scans.According to pathological results,the patients were divided into MVI group(24 cases)and non MVI group(56 cases),and the differences in MRI multi sequence imaging features and related parameters between the two groups were compared.the influencing factors of MVI were determined by Logistic regression model,and the diagnostic efficacy of influencing factors on MVI was evaluated by receiver operating characteristic curve(ROC).Results The incidence of MVI in IMCC patients in this study was 30.00％.The tumor diameter and apparent diffusion coefficient(ADC)in the MVI group were significantly higher than those in the non MVI group(P＜0.05);There was no difference between the two groups in tumor morphology,T1 weighted imaging(T1WI)and T2 weighted imaging(T2WI)signals,presence or absence of necrosis,enhancement mode,diffusion weighted imaging(DWI)signals,presence or absence of targets,capsule contracture,and bile duct dilation(P＞0.05).Using multivariate logistic regression analysis,it was found that ADC value was an independent risk factor for MVI in IMCC patients(P＜0.05).By analyzing the ROC curve,it was found that the Area under the curve(AUC)of predicting MVI in IMCC patients with ADC values was 0.903,with sensitivity of 92.36％,specificity of 88.79％,and 95％CI of 85.66％-98.87％;the optimal cutoff threshold is 1.45×10-3mm2/s.Condusion MRI multiple sequences have good diagnostic efficacy in predicting the MVI status of IMCC patients,with ADC values serving as independent risk factors for predicting the occurrence of MVI,which helps to provide more valuable preoperative information for precise medical treatment of IMCC patients.
Magnetic Resonance ImagingIntrahepatic Mass-forming CholangiocarcinomaMicrovascular InvasionPredictive Value
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