Clinical Value of Multi-slice Spiral CT Enhancement Combined with Dynamic Contrast-enhanced Magnetic Resonance Functional Imaging in Evaluating Postoperative Local Recurrence/Metastasis of Colorectal Cancer
Objective To investigate the clinical value of multislice spiral CT enhancement combined with dynamic enhanced magnetic resonance functional imaging for the evaluation of local recurrence/metastasis after colorectal cancer(CRC)surgery.Methods Eighty-two CRC patients admitted to our hospital between October 2019 and October 2021 were selected and divided into the recurrence or metastasis group(36 patients)and the non-recurrence or metastasis group(46 patients)according to their postoperative conditions;all patients underwent multilayer spiral CT-enhanced and dynamically-enhanced magnetic resonance functional imaging;ROC curves were plotted to analyse the diagnostic value of multilayer spiral CT-enhanced and transport constant(Ktrans),reflux rate constant(Kep),and extracellular volume fraction(Ve)on the diagnostic value of local recurrence/metastasis after CRC;a four-cell table was used to analyse the diagnostic value of multilayer spiral CT enhancement combined with dynamic enhanced magnetic resonance functional imaging to evaluate the diagnostic value of local recurrence/metastasis after CRC.Results Multi-slice spiral CT enhanced scanning showed that among the 39 positive patients examined,30 had recurrence or metastasis,9 had no recurrence or metastasis,and among the 43 negative patients examined,6 had recurrence or metastasis,and 37 had no recurrence or metastasis.The Ktrans,Kep,and Ve levels in the recurrent or metastatic group were obviously higher than those in the non recurrent or metastatic group(P＜0.05).According to the ROC curve,the area under the curve(AUC)of Ktrans to diagnose local recurrence/metastasis of CRC after surgery was 0.846,the AUC of Kep to diagnose local recurrence/metastasis of CRC after surgery was 0.780,the AUC of Ve to diagnose local recurrence/metastasis of CRC after surgery was 0.861,the AUC of multi-slice spiral CT enhanced diagnosis for postoperative local recurrence/metastasis of CRC was 0.819,the AUC for the combined diagnosis of local recurrence/metastasis after CRC surgery was 0.987.The accuracy of multislice spiral CT enhancement in the diagnosis of local recurrence/metastasis after CRC was 81.71％;the accuracy of dynamic enhanced magnetic resonance functional imaging in the diagnosis of local recurrence/metastasis after CRC was 85.37％;and the accuracy of combined detection of the two in the diagnosis of local recurrence/metastasis after CRC was 93.90％.Condusion Multislice spiral CT enhancement combined with dynamic enhanced magnetic resonance functional imaging can significantly improve the diagnostic efficacy of local recurrence/metastasis after CRC surgery,and is of high clinical value for patients in postoperative follow-up monitoring.
Multi Slice Spiral CT EnhancementDynamic Enhanced Magnetic Resonance Functional ImagingColorectal CancerRecurrenceMetastasisDiagnosis
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