Advances in Imaging Research of Traumatic Brain Injury
After traumatic brain injury(TBI),there is a dynamic development area around the primary lesion,which can return to normal or turn into irreversible injury,which is called contusion penumbra(CP).At present,the pathophysiological changes of the traumatic penumbra are not clear.Studies suggest that the main physiological changes in this region include changes in cerebral blood flow,cerebral edema,apoptosis and necrosis,etc.The development of traumatic penumbra is closely related to the prognosis of patients,which is the focus of clinical observation and treatment.Currently,multi-mode magnetic resonance technology has a plethora of ways to observe the trauma penumbra,such as diffusion-weighted imaging,magnetic sensitive weighted imaging,perfusion weighted imaging,diffusion tensor imaging,diffusion kurtosis imaging,hydrogen proton spectroscopy imaging,and quantitative magnetic sensitive imaging.There are also a variety of methods to define the scope of the trauma penumbra,but there is no unified conclusion on the definition method.A review of the penumbra's pathophysiological alterations and imaging research advancement in traumatic brain injury is presented in this article.
Traumatic Brain injuryTraumatic PenumbraMultimodal Magnetic Resonance
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