Research Progress of Intravoxel Incoherent Motion Diffusion-weighted Imaging in Endometrial Carcinoma
Endometrial cancer is one of the common gynecological malignant tumors in our country.Early lesions can be effectively treated by surgery and generally do not require adjuvant therapy,but the treatments of high-risk and advanced diseases are more complicated.The formulation of treatment plan is generally related to the preoperative pathological diagnosis,histological type,age and fertility requirement of patients.Molecular typing has provided us with a deeper understanding of heterogeneity,which is of great significance in predicting prognosis,assessing recurrence risk,guiding treatment and genetic screening.IVIM adopts multi-B-value imaging,and its derived parameters can comprehensively reflect the microscopic conditions of the tumor from different angles,and then obtain the information of internal diffusion movement and microcirculation perfusion at the same time.ln this review,we summarized the principle of IVIM and its application value in tissue typing and molecular typing,tumor grading and depth of invasion,preoperative risk stratification,and differential diagnosis of endometrial cancer,providing data support for accurate diagnosis and individualized treatment of patients with endometrial cancer.
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