摘要
目的 探讨肺泡蛋白沉积症(PAP)的CT表现,以提高对该病的CT诊断水平.方法 收集并整理16例穿刺活检或/和肺泡灌洗确诊的PAP患者病例,将其CT表现进行分析总结,并文献复习.结果 PAP肺部阴影重而临床症状轻微,CT表现多样化,可表现为双肺广泛不呈叶段分布的斑片状磨玻璃密度影、铺路石征、地图征、蝶翼征、支气管充气征、肺实变及肺间质纤维化等;"铺路石征"、"地图征"同时出现,临床症状、体征与CT表现不一致时,强烈提示本病.结论 PAPCT表现具特征性,结合临床可与肺炎、肺水肿、肺炎型肺癌、弥漫性肺泡出血及特发性肺间质纤维化等其他肺部病变相鉴别.
Abstract
Objective To explore the CT findings of pulmonary alveolar proteinosis(PAP)in order to improve the CT diagnosis of the disease.Methods Sixteen cases of patients with PAP diagnosed by puncture biopsy were collected and compiled,and their CT manifestations were analyzed and summarized in a literature review.Results PAP has severe lung shadow and mild clinical symptoms,and its CT manifestations are diverse,which can be manifested as patchy ground-glass density shadow,paving stone sign,map sign,butterfly wing sign,bronchial inflation sign,lung consolidation and pulmonary interstitial fibrosis,etc;"Paving stone sign"and"map sign"appear at the same time,when the clinical symptoms and signs are inconsistent with CT findings,it strongly suggests the disease.Conclusion PAPCT manifestations are characteristic and can be differentiated from other lung lesions such as pneumonia,pulmonary edema,pneumonic lung cancer,diffuse alveolar hemorrhage and idiopathic interstitial fibrosis in conjunction with the clinic.
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