首页|CCTA斑块定量分析在冠心病患者冠状动脉斑块特征的临床价值

CCTA斑块定量分析在冠心病患者冠状动脉斑块特征的临床价值

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目的 探究冠状动脉CT血管造影(CCTA)斑块定量分析在评估冠心病患者冠状动脉斑块特征中的临床价值.方法 选取本院2019年6月-2022年6月收治的90例冠心病患者,所有患者均行CCTA和冠状动脉造影(CAG)检查,CAG为"金标准",对比两种方法检查冠状动脉斑块特征(斑块位置、斑块长度、钙化斑块体积、非钙化斑块体积、斑块负荷)、冠脉重塑指数和狭窄程度的结果.随访患者1年内主要不良心血管事件(MACE)的发生情况.采用ROC分析CCTA斑块定量分析指标对患者预后的评估价值.结果 CCTA检查和CAG检查的斑块和冠脉特征比较,差异无统计学意义(P>0.05);随访1年后,患者MACE发生15例,发生率为16.67%.MACE组患者的冠脉斑块特征指标(非钙化斑块体积、斑块负荷)、冠脉重塑指数和狭窄程度均高于非MACE组,差异有统计学意义(P<0.05);患者ROC曲线结果显示,重塑指数(AUC=0.731)、狭窄程度(AUC=0.676)、非钙化斑块体积(AUC=0.729)和斑块负荷(AUC=0.699)均对冠心病患者的预后具有预测价值(P<0.05).结论 CCTA斑块定量分析技术可以有效评估冠心病患者冠状动脉斑块特征,预测患者的预后.
Clinical Evaluation Value of CCTA Plaque Quantitative Analysis in Characteristics of Coronary Artery Plaques in Patients with Coronary Heart Disease
Objective To explore the clinical evaluation value of coronary CT angiography(CCTA)plaque quantitative analysis in characteristics of coronary artery plaques in patients with coronary heart disease(CHD).Methods A total of 90 patients with CHD in the hospital were enrolled between June 2019 and June 2022.All underwent CCTA and coronary angiography(CAG).Taking CAG as the golden standard,evaluation results of coronary plaque characteristics(plaque sites,plaque length,volume of calcified plaque,volume of non-calcified plaque,plaque load),coronary remodeling index and stenosis degree by the two methods were compared.The occurrence of major adverse cardiac events(MACE)within 1 year was followed up.The evaluation value of CCTA plaque quantitative analysis indexes for prognosis was analyzed by ROC curves.Results There was no significant difference in plaques or coronary characteristics between CCTA and CAG(P>0.05).After 1 year of follow-up,there were 15 cases(16.67%)with MACE.The characteristics of coronary artery plaques(volume of non-calcified plaque,plaque load),coronary remodeling index and stenosis degree in MACE group were higher than those in non-MACE group(P<0.05).The results of ROC curves analysis showed that remodeling index(AUC=0.731),stenosis degree(AUC=0.676),volume of non-calcified plaque(AUC=0.635)and plaque load(AUC=0.699)were of predictive value for prognosis of CHD patients(P<0.05).Conclusion CCTA plaque quantitative analysis can effectively evaluate the characteristics of coronary artery plaques and predict prognosis of CHD patients.

Coronary CT AngiographyCoronary Artery PlaqueCoronary Heart Disease

袁伟、冯军鹏

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三二○一医院医学影像科(陕西汉中 723000)

铜川市人民医院心血管内科(陕西铜川 727000)

冠状动脉CT血管造影 冠状动脉斑块 冠心病

陕西省重点研发计划

2021SF-044

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(8)