Clinical Value of DWI,T2WI and Dynamic Contrast-enhanced MRI in Diagnosing Small Hepatocellular Carcinoma under the Background of Liver Cirrhosis
Objective To investigate the clinical value of diffusion weighted imaging(DWI),T2 weighted imaging(T2WI)and dynamic contrast-enhanced magnetic resonance imaging(MRI)in diagnosing small hepatocellular carcinoma(sHCC)under the background of liver cirrhosis.Methods The DWI,T2WI and dynamic contrast-enhanced MRI data of 62 patients who were suspected of sHCC in liver cirrhosis and admitted to the hospital from February 2019 to February 2023 were analyzed retrospectively.Referring to histopathological results,the diagnostic value of the three for sHCC under the background of liver cirrhosis was evaluated.Results Histopathological results showed that there were 38 patients with sHCC and 24 patients without.Referring to histopathological results,the diagnostic sensitivity,specificity,accuracy,positive and negative predictive values,and Kappa value of DWI for sHCC under the background of liver cirrhosis were 84.21％,83.33％,83.87％,88.89％,76.92％and 0.665.The diagnostic sensitivity,specificity,accuracy,positive and negative predictive values,and Kappa value of T2WI were 76.32％,66.67％,72.58％,78.38％,64.00％and 0.427.The diagnostic sensitivity,specificity,accuracy,positive and negative predictive values,and Kappa value of dynamic contrast-enhanced MRI were 86.84％,66.67％,79.03％,80.49％,76.19％and 0.548.There was no statistically significant difference among the three methods in the sensitivity,specificity,accuracy,positive and negative predictive values for diagnosing sHCC under the background of liver cirrhosis.Conclusion DWI,T2WI and dynamic contrast-enhanced MRI have similar diagnostic performance and can be used as auxiliary clinical diagnostic methods for sHCC under the background of liver cirrhosis.
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