CT Diagnosis of Abdominal Mature B-cell Non-Hodgkin Lymphoma in Children
Objective To investigate the CT and immunohistochemical features of mature abdominal B-cell non-Hodgkin lymphoma in children.Methods CT findings and immunohistochemical findings of 17 cases of abdominal mature B-cell non-Hodgkin lymphoma were retrospectively analyzed.All the tumors were confirmed by operation and pathology.Results All the 17 cases were boys,aged from 3 to 10 years,with a median age of 5 years and 9 months.1 case showed gastric wall thickening and mass;the thickness of intestinal wall varied in 16 cases,including 13 cases with moderate or obvious thickening,11 cases with mass as the main manifestation,10 cases with diameter greater than 50mm;imaging manifestations include peritoneal thickening,increased mesenteric space fat density,intestinal aneurysmal dilatation,sandwich sign,abdominal lymph node enlargement,intussusception,abdominal pelvic effusion,parenchymal organ involvement,and extrabdominal metastasis.Tumor cells often express CD19,CD20,CD22,CD79a in immunohistochemistry,and Bcl-2 negative is also one of its characteristics.Conclusion Mature abdominal B-cell non-Hodgkin lymphoma in children has certain imaging features,such as intestinal wall thickening,intestinal mass,diffuse peritoneal mesangial thickening,etc.Combined with immunohistochemistry,it indicates mature abdominal B-cell non-Hodgkin lymphoma.
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