The Value of Contrast-enhanced CT in Predicting Lymph Node Metastasis of Gastrointestinal Neuroendocrine Tumors
Objective To investigate the value of contrast-enhanced(CE)computed tomography(CT)in predicting lymph node metastasis(LNM)of gastrointestinal neuroendocrine tumors(GINTs).Methods The CECT manifestations of 33 cases with GINTs confirmed by postoperative pathology were retrospectively analyzed.The qualitative differences and quantitative differences between the groups with and without LNM were compared.The chi-square test,Fisher's exact test,Mann-Whitney U test and Logistic regression analysis were performed.Results There were no statistically significant differences in the necrosis of GINTs,the invasion of the inner and outer walls,the degree of enhancement,the uniformity of enhancement,stratified enhancement,lymphadenectasis,and distant metastasis between the groups.The CT parameters of VPmax(P=0.035),VPmean(P=0.043),VPmean-NP(P=0.015),and VPmean-NP/NP(P=0.011)were significantly different between groups.According to receiver operating characteristic(ROC)curve analysis,the areas under the ROC curves of CT parameters of VPmax(P=0.035),VPmean(P=0.043),VPmean-NP(P=0.015),and VPmean-NP/NP(P=0.011)were 0.741,0.731,0.778 and 0.792,respectively.The diagnostic efficiency of VPmean-NP/NP is the best.Conclusion CECT has certain value in predicting LNM of GINTs.