摘要
目的 探讨增强CT在预测胃肠道神经内分泌肿瘤淋巴结转移中的价值.方法 回顾性分析33例经手术病理证实的胃肠道神经内分泌肿瘤的增强CT的表现,比较有淋巴结转移组与非淋巴结转移组的定性差异及测量其相关CT值的定量差异,并对其进行卡方检验、Fisher精确性检验、Mann-Whitney U检验及Logistic回归分析.结果 胃肠道神经内分泌肿瘤是否坏死、内壁外壁是否受侵犯、强化程度、强化均匀度、分层强化、淋巴结转移及远处转移在组间均无显著统计学差异.静脉期最大CT值(P=0.035)、静脉期平均CT值(P=0.043)、静脉期-平扫CT值(P=0.015)、静脉期-平扫CT值除以平扫CT值(P=0.011)组间差异具有统计学意义.ROC曲线分析,得出静脉期最大CT值、静脉期平均CT值、静脉期-平扫CT值、静脉期-平扫CT值除以平扫CT值在参数的曲线下面积其AUC值分别约为0.741、0.731、0.778、0.792,静脉期-平扫CT值除以平扫CT值诊断效能最好.结论 增强CT部分参数在预测胃肠道神经内分泌肿瘤淋巴结转移上具有一定价值.
Abstract
Objective To investigate the value of contrast-enhanced(CE)computed tomography(CT)in predicting lymph node metastasis(LNM)of gastrointestinal neuroendocrine tumors(GINTs).Methods The CECT manifestations of 33 cases with GINTs confirmed by postoperative pathology were retrospectively analyzed.The qualitative differences and quantitative differences between the groups with and without LNM were compared.The chi-square test,Fisher's exact test,Mann-Whitney U test and Logistic regression analysis were performed.Results There were no statistically significant differences in the necrosis of GINTs,the invasion of the inner and outer walls,the degree of enhancement,the uniformity of enhancement,stratified enhancement,lymphadenectasis,and distant metastasis between the groups.The CT parameters of VPmax(P=0.035),VPmean(P=0.043),VPmean-NP(P=0.015),and VPmean-NP/NP(P=0.011)were significantly different between groups.According to receiver operating characteristic(ROC)curve analysis,the areas under the ROC curves of CT parameters of VPmax(P=0.035),VPmean(P=0.043),VPmean-NP(P=0.015),and VPmean-NP/NP(P=0.011)were 0.741,0.731,0.778 and 0.792,respectively.The diagnostic efficiency of VPmean-NP/NP is the best.Conclusion CECT has certain value in predicting LNM of GINTs.
基金项目
山东省医药卫生科技发展计划(2021030110741)
NETL
NSTL
万方数据