The Value of Semiquantitative 99mTc-MDP Whole Body Bone Tomography Fusion Imaging in Identifying Bone Metastasis Lesions of Prostate Cancer
Objective Explore the value of semi quantitative 99mTc MDP whole body bone tomographic fusion imaging in identifying bone metastases from prostate cancer.Methods 80 patients with prostate cancer were selected from our hospital from May 2021 to May 2023.Postoperative pathology showed 54 patients with prostate cancer bone metastasis and 26 patients without bone metastasis.All patients underwent 99mTc MDP whole body bone tomographic fusion imaging with semi quantitative technique.The image analysis was independently completed by one attending physician and one Chief physician.The average standardized uptake value(SUVmean)and maximum standardized uptake value(SUVmax)can be obtained through QMetrix analysis.Compare the changes in serum prostate specific antigen(PSA),SUVmean,and SUVmax between the bone metastasis group and the non bone metastasis group;To analyze the accuracy,Sensitivity and specificity of 99mTc MDP whole body bone tomography fusion imaging in the diagnosis of bone metastasis;Pearson analyzed the correlation between PSA and SUVmean and SUVmax.Results The bone metastasis group serum PSA level higher than non bone metastasis group(P＜0.05).The bone metastasis group SUVmean and SUVmax values higher than non bone metastasis group(P＜0.05).The accuracy of 99mTc MDP whole body bone tomographic fusion imaging in diagnosing bone metastasis was 88.89％(48/54).The sensitivity and specificity of 99mTc-MDP whole body bone tomographic fusion imaging in diagnosing bone metastasis were 79.63％and 80.77％,respectively.Pearson correlation analysis showed that PSA showed a linear positive correlation with SUVmean and SUVmax(P＜0.05).Conclusion The semi quantitative technique of 99mTc MDP whole body bone tomographic fusion imaging has a high diagnostic accuracy for bone metastases of prostate cancer,and has good Sensitivity and specificity,which is worthy of clinical reference.
99mTc MDP Whole Body Bone Tomographic Fusion imaging Semi Quantitative TechniqueProstate CancerBone Metastasis Lesion
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