The Magnetic Resonance Imaging Features in Glioma:Association with IDH1 Mutation
Objective The present study detected the isocitrate dehydrogenase 1(IDH1)to analyze the correlation with magnetic resonance imaging(MRI)characteristics in glioma.Methods A total of 116 gliomas were included.All patients underwent conventional MRI before operation and contrast-enhanced T1-weighted imaging,the observations were as follows:location,size,the pattern of growth,margin,signal intensity,reinforcement level,mass effect,edema,cross the mid-line,under the ependyma.Results IDH1 mutant glioma was associated with the following magnetic resonance characteristics,including tumor location(P=0.001),pattern of growth(P=0.003),margin(P=0.005),signal intensity(P=0.009),contrast enhancement(P=0.000),there were statistically significant.Conclusion The MRI features of IDH-1 mutated gliomas were located in a single lobe,such as the frontal and temporal lobe.Gliomas with IDH mutations were significantly more likely to exhibit a unilateral pattern of growth,sharp margins,homogeneous signal intensity and less contrast enhancement.
万方数据
维普
