Study on the Level of Collateral Circulation and Prognosis of Acute Ischemic Stroke with 4DCTA-CTP Combined with Serum S100B Technique
Objective To evaluate the lateral cerebral circulation in patients with acute ischemic stroke(AIS)by four-dimensional CT angiography and CT perfusion(4DCTA-CTP),and to explore the feasibility of predicting the prognosis of AIS patients with lateral cerebral circulation and serum S100B protein concentration.Methods The clinical data of 32 patients with anterior circulation AIS treated with 4DCTA-CTP were retrospectively analyzed.Multiphase CT angiography(MCTA)score and local pia collateral circulation(RLMC)score were used to evaluate the level of collateral circulation.Combined with serum S100B protein concentration,multivariate binary Logistic regression analysis was performed to find indicators that could independently predict the prognosis of AIS nerve function.Results Univariate analysis showed that NIHSS score,rLMC score and MCTA score were correlated with the neurological prognosis of AIS patients,and multivariate analysis showed that MCTA collateral circulation score was the only indicator that could independently predict the neurological prognosis of AIS patients(OR=0.065,P=0.030).Baseline serum S100B protein concentration does not independently predict neurological outcomes in AIS patients.Conclusion MCTA collateral circulation score can independently predict the neurological prognosis of AIS patients.For evaluating the neurological prognosis of AIS patients,the temporal score of the lateral cerebral circulation is superior to the local score.
万方数据
维普
