Evaluated Value of CTP Combined with CTA on Blood Perfusion in the Surrounding Tissue of Traumatic Brain Injury Lesions
Objective To explore the evaluated value of CT perfusion imaging(CTP)combined with CT angiography(CTA)on blood perfusion in the surrounding tissues of traumatic brain injury(TBI)lesions.Methods The data of 80 patients with TBI in our hospital were analyzed retrospectively.CTP,CTA and digital subtraction angiography(DSA)were performed on all patients,the surgical pathology and DSA were used as the gold standard,and the detection status of lesions by CTP and CTA and CTP parameters[cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT),time to peak(TTP)]in lesion area and contralateral area were compared.The detection status of lesion surrounding vascular stenosis degree in patients with TBI by CTA was analyzed,and Pearson correlation coefficient was used to analyze the correlation between CTP parameters and GCS score.Results Among the 80 patients,there were 42 cases of intracranial injury,28 cases of extraaxial injury and 10 cases of deep brain injury by surgical pathological diagnosis.The clinical detection rates of CTP and CTA were 96.25％and 93.75％respectively.The CBV and CBF in the lesion area were significantly lower than those in the contralateral area(P＜0.05),and the MTT and TTP were significantly longer than those in the contralateral area(P＜0.05).89 sites of vascular stenosis were detected in 80 patients diagnosed by DSA,including 45 mild stenosis,26 moderate stenosis,15 severe stenosis and 3 occlusion.The accuracy rates of mild,moderate,severe and occlusive vessels detected by CTA were 97.73％,82.14％,85.71％and 100％respectively,with a total accuracy rate of 91.01％.Pearson correlation coefficient analysis showed that GCS score were positively correlated with CTP parameters CBF and CBV,and were negatively correlated with MTT and TTP(P＜0.05).Conclusion CTP and CTA can better feedback the cranial hemodynamics and vascular lesions in patients with TBI.The combined examination of CTP and CTA can provide important information for the clinical diagnosis of patients with TBI to assist clinical treatment.
万方数据
维普
