The Application Value of CTP Imaging Parameters in Evaluating the Reactivity of Conservative Treatment in Patients with Severe Carotid Arterv Stenosis
Objective To evaluate the value of CT perfusion imaging(CTPI)factor for measuring conservative treatment response in patients with severe carotid artery stenosis(CAS).Methods 193 patients with severe carotid artery stenosis who received conservative treatment from March 2019 to July 2023 were selected and classified into high-risk group(n=106)and low-response group(n=87)according to whether ischemic brain disease occurred or not.The CTP imaging parameters rMTT,rTTP,rCBV and rCBF of each group were compared,and the pathological diagnosis results were taken as the standard.Multifactor logistic regression analysis was conducted on the influencing factors of the occurrence of cerebral ischemic disease in CAS patients undergoing conservative treatment.Also for conservative treatment in patients with severe ioc in ischemic brain CTP imaging diagnosis of factor analysis and measuring value.Results Age,gender,hyperlipidemia,complications of coronary atherosclerosis,smoking history,etc.had no obvious difference between the two groups(P＞0.05),however,hypertension,diabetes complications,rMTT,rTTP were significantly higher than those in the hyperresponsive group(P＜0.05),and rCBV,rCBF were significantly lower(P＜0.05).With hypertension,diabetic complications,low rMTT,rTTP,high rCBV and rCBF were risk factors for the development of ischemic cerebral diseases(P＜0.05).Screening of conservative treatment responses in patients with severe carotid angina with CTP imaging parameters rMTT,rTTP,rCBV and rCBF were more sensitive and accurate than those 4 individual tests(P＜0.05).Conclusion The application of CTPI parameters in evaluating conservative treatment responsiveness in patients with severe carotid artery stenosis is worthy of widespread dissemination clinically.
万方数据
维普
