Application of Low-dose CT in Pulmonary Nodule Screening and Establishment of Prediction Model
Objective To analyze the screening effect of low-dose CT in patients with pulmonary nodules and its predictive value for high-risk lesions.Methods Analyze the clinical data of 80 patients with pulmonary nodules admitted to our hospital from November 2022 to August 2023.All patients underwent LDCT examination,and the predictive value of this examination method for high-risk lesions in patients with pulmonary nodules was analyzed.Results There were statistically significant differences in the parameters of nodule diameter,nodule location,ground glass nodule,solid nodule,calcification sign,tracheal aeration sign,pleural sag sign,burr sign,lobed sign,total nodule perfusion volume,pulmonary artery perfusion value and bronchial artery perfusion value in patients with different nodule characteristics(P<0.05).The above indicators were included in the Logistic regression analysis model,and the results showed that the nodules with diameter>2cm,were ground glass nodules,had trachea aeration sign,burr sign,and lobed sign,total nodule perfusion volume,and bronchial artery perfusion value were independent influencing factors for high-risk nodules(P<0.05).ROC curve analysis based on the combined prediction data showed that the predicted AUC was 0.992;The prediction sensitivity was 99.2%and the specificity 94.0%.Conclusion LDCT has high value and diagnostic accuracy in detecting pulmonary nodules,and high predictive probability for malignant lesions.