Diagnostic Value of Enhanced CT Combined with Serum DSG2 in Esophageal Squamous Cell Carcinoma
Objective To investigate the diagnostic value of enhanced CT combined with serum desmoglein 2(DSG2)in esophageal squamous cell carcinoma(ESCC).Methods Retrospective analysis of the clinical data of 68 ESCC patients(ESCC group)and 42 esophageal leiomyoma patients(esophageal leiomyoma group)admitted to our hospital from January 2020 to December 2022,all of whom underwent enhanced CT examination and serum DSG2 level detection.Compare the differences in enhanced CT features and serum DSG2 levels between the two groups.The efficacy of enhanced CT features and serum DSG2 levels in the diagnosis of ESCC was analyzed by drawing the receiver operating characteristic curve(ROC).Results The proportion of tumors located in the middle thoracic segment of the esophagus,with an area exceeding 1/2 of the esophageal wall,unsmooth edges,unclear peripheral spaces,and lymph node metastasis,and the level of serum DSG2 in the ESCC group were significantly higher than those in the esophageal leiomyoma group(P＜0.05).However,there was no statistically significant difference between the ESCC group and the esophageal leiomyoma group in the enhancement pattern,necrotic regions,and the proportion of ulcers(P＞0.05);Compared with individual diagnosis,enhanced CT features combined with serum DSG2 levels have the highest AUC,Yoden index,sensitivity,and specificity for ESCC evaluation.Conclusion Enhanced CT features combined with serum DSG2 levels have higher evaluation value in the diagnosis of ESCC,providing evidence for clinical diagnosis and treatment.
Enhanced CTSerum Desmoglein 2Esophageal Squamous Cell CarcinomaDiagnostic Value
万方数据
维普
