Comparative Study of Energy Spectrum CT and Ultrasonography to Evaluate the Efficiency of DEB-TACE in Hepatocellular Carcinoma
Objective Comparative analysis of energy spectrum CT and ultrasonography in evaluating the efficacy assessment after DEB-TACE for hepatocellular carcinoma.Methods 38 patients with hepatocellular carcinoma who underwent DEB-TACE at the Department of Radiological Intervention of the First Affiliated Hospital of Zhengzhou University were prospectively enrolled,and all of them underwent CT energy spectral scanning and acoustic imaging for efficacy assessment 4 to 6 weeks after DEB-TACE,and DSA within 7 days after the end of the examination.DSA results were used as the gold standard to analyze the difference in the efficacy of DEB-TACE for hepatocellular carcinoma assessed by energy spectrum CT and ultrasonography.SPSS21.0 software was used for statistical analysis to calculate the sensitivity,specificity,leakage rate,misdiagnosis rate,and Jordon's index of the two methods,and MedCalc plotted the ROC curves to compare the test efficacy of the two examination methods by comparing the AUC.Results The results of spectral CT for diagnosing residual cancer or recurrence:sensitivity 93.33％,specificity 100.0％,misdiagnosis rate 0.0％,leakage rate 6.67％,correct rate 94.74％,and Yoden index 93.33％.The results of ultrasonography in diagnosing residual cancer or recurrence:sensitivity 76.67％,specificity 100.00％,misdiagnosis rate 0％,leakage rate 23.33％,correct rate 81.58％,and Yoden index 76.67％.The area under the curve of energy spectrum CT and acoustic imaging were 0.967 and 0.883,respectively,and there was a significant difference between the two comparisons(P＜0.05).Conclusion Compared with acoustic imaging,energy-spectrum CT is more accurate in evaluating the efficacy of DEB-TACE in hepatocellular carcinoma,and is valuable in the evaluation of patient outcomes after hepatocellular DEB-TACE.
万方数据
维普
