Diagnostic Value of Combined Ultrasound and CT Enhancement with Tumor Markers AFP and CA199 in HCC
Objective Early screening and diagnosis are important for the treatment and prognosis of patients with liver cancer.The aim of this study was to investigate the utility of the combination of contrast-enhanced and contrast-enhanced CT with the tumor markers AFP and CA199 in the diagnosis of HCC.Methods We retrospectively analyzed the clinical data of the HCC(n=256),benign disease(n=110),and control(n=50)patients who were admitted to our hospital between June 2020 and June 2022.The HCC and benign disease groups were pathologically diagnosed with CEUS and contrast-enhanced CT before operation,and serum AFP and CA199 contents were detected by Electrochemiluminescence Method,and ROC curves were drawn.Results The detection rate of contrast-enhanced ultrasound was higher than that of contrast-enhanced CT.The serum levels of AFP and CA199 in the HCC group were significantly higher than those in the patients with benign lesions and the control group.ROC curves showed that the sensitivity,accuracy,and negative predictive rate of ultrasound and enhanced CT combined with tumor markers AFP and CA199 for HCC diagnosis were significantly higher than single tests.Condusion The combined detection of contrast-enhanced CT,AFP,and CA199 significantly increased the sensitivity and accuracy of HCC diagnosis.It has a significant effect on the early diagnosis of HCC and can be used as an important means of early screening.
UltrasoundContrast-enhanced CTAFPCA199Liver Cancer
万方数据
维普
