Clinical Value of Abdominal DCE-MRI Combined with IVIM in the Diagnosis of Endometrial Lesions
Objective To evaluate the clinical value of abdominal dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with intravoxel incoherent motion imaging(IVIM)in the diagnosis of endometrial lesions.Methods Eighty-two patients with endometrial lesions who underwent MRI in our hospital from January 2022 to February 2023 were selected,and categorized into benign group(n=49)and malignant group(n=33)using pathological findings as the gold standard.The DCE-MRI and IVIM parameters were compared between two groups,and receiver operating characteristic curve(ROC)was plotted to evaluate the diagnostic value of DCE-MRI combined with IVIM in detecting endometrial lesions.Results The values of volume transfer constant(Ktrans),rate transfer coefficient(Kep)and extravascular extracellular volume fraction(Ve)of benign group were smaller than those of malignant group(P＜0.05).The apparent diffusion coefficient(ADC)of pure diffusion(ADC-slow),perfusion fraction(f),distributed diffusion coefficient(DDC)and diffusion heterogeneity index(α)of benign group were larger than those of malignant group,while the ADC of pseudo-diffusion(ADC-fast)was smaller than that of malignant group(P＜0.05).ROC curve indicated that an area under the curve(AUC)of 0.812,0.762,0.736,0.726,0.666,0.706,0.686 and 0.777 for Ktrans,Kep,Ve,ADC-slow,ADC-fast,f,DDC and a in detecting endometrial lesions provided the largest Youden index.A cutoff value of 0.45,0.86,0.51,0.47,12.69,0.37,1.02 and 0.66 for Ktrans,Kep,Ve,ADC-slow,ADC-fast,f,DDC andα resulted in an AUC,sensitivity,specificity,positive predictive value and negative predictive value of 0.894(95％CI:0.812～0.975),84.8％,93.9％,93.4％and 86.2％,suggesting that the combined test had better diagnostic efficacy than that of separate test(P＜0.05).Condusion The combined application of abdominal DCE-MRI and IVIM can improve the diagnostic accuracy of endometrial lesions and is of great clinical value.
万方数据
维普
