首页|基于QCT探究腰椎骨密度、肝脏脂肪含量及血尿酸水平的相关性

基于QCT探究腰椎骨密度、肝脏脂肪含量及血尿酸水平的相关性

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目的 基于QCT(quantitative computed tomography)对腰椎骨密度(bone mineral density,BMD)、腹内脂肪面积(visceral fat area,VFA)、肝脏脂肪含量以及血尿酸(serum uric acid,SUA)的相关性进行研究分析.方法 选取本院2022年6月至2022年12月行中上腹部扫描的住院中老年患者233例,年龄41-80岁,其中男性119人,女性114人;对以上纳入研究人群的年龄、体重、身高、SUA等项目数据进行收集及整理,并计算出对应的体质指数(BMI);采用GE 256排Revolution CT扫描仪,并应用QCT测量软件测量腰椎骨密度、肝脏脂肪含量、VFA.结果 腰椎BMD与SUA呈正相关,与肝脏脂肪含量、年龄、VFA呈负相关,P<0.05,均具有统计学意义;肝脏脂肪含量与年龄、BMI、VFA、SUA呈正相关,P<0.05,其统计学差异均具有意义;SUA与VFA、BMI呈正相关,P<0.05,均具有统计学意义.结论 肝脏脂肪含量及年龄是影响腰椎BMD的危险性因素,SUA可能是影响骨代谢的保护性因素.随着SUA水平的升高,肝脏脂肪含量也随之增加,可能SUA是非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)发生的独立危险因素.
Correlation Analysis Of Lumbar Bone Mineral Density Liver Fat Content and Serum Uric Acid Level Assessed byQCT
Objective The correlation analysis of lumbar bone mineral density,liver fat content,visceral fat area and serum uric acid level were analyzed based on QCT.Methods A total of 233 hospitalized middle-aged and elderly patients aged 41-80 years from June 2022 to December 2022 were selected,including 119 males and 114 females;general data such as age,height weight,body mass index and serum uric acid were collected;middle and upper abdomen were scanned with GE 256-row Revolution CT scanner,and then lumbar bone mineral density,liver fat content and visceral fat area were measured by QCT measurement software.Results Lumbar BMD was negatively correlated with age,liver fat area and visceral fat area,and positively correlated with serum uric acid,P<0.05,and the difference was statistical significance;Liver fat content was positively correlated with age,BMI,serum uric acid and visceral fat area,P<0.05,and the difference was statistically significant.Serum uric acid was positively correlated with visceral fat area and BMI,P<0.05,and the difference was statistically significant.Conclusion Age and liver fat content are risk factors affecting bone mineral density,and serum uric acid may be a protective factor affecting bone metabolism.With the increase of liver fat content,serum uric acid may be an independent risk factor for NAFLD.

Bone Mineral DensityLiver Fat ContentSerum Uric AcidVisceral Fat Area

赵敏、党计锋、王国华、杨雅晴、郝天琦、黄小铭、曲雪廷

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青岛大学青岛市市立医院放射科(山东靑岛 266011)

青岛西海岸新区区立医院放射科(山东青岛 266400)

青岛大学附属青岛市海慈医院(青岛市中医医院)放射科(山东靑岛 266033)

骨密度 肝脏脂肪含量 血尿酸 腹内脂肪面积

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(9)
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