Prognostic Study of CT Plain Scan and CT Perfusion Imaging in Thrombolytic Therapy of Acute Ischemic Stroke
Objective High-density vascular signs(HDVS)on the Alberta Stroke Program early CT score(ASPECTS)and baseline noncontrast CT(NCCT)may be beneficial for the prognosis of acute ischemic stroke(AIS).The objective of this study was to evaluate the prognosis of plain CT scan and perfusion CT imaging in AIS thrombolytic therapy.Methods Clinical data of AIS patients treated with thrombolytic therapy from September 2018 to September 2023 who underwent NCCT and perfusion imaging before treatment were retrospectively analyzed.The predictive value of clinical risk factors,NCCT and CTP results was evaluated by univariate,multifactorial and receiver operating characteristics(ROC)analysis.Results Of the 75 patients included in this study,35(46.7％)had a good prognosis.In multivariate analysis,ASPECTS,HDVS,infarct volume and mismatch rate were univariate correlated with functional outcomes,while infarct volume remained an independent prognostic factor.The area under ROC(AUC)of the multivariate model was 0.768(95％CI,0.666-0.870).Conclusion Automatic Aspects are basically consistent with reference CTP-Aspects assessment,and comprehensive CT assessment may contribute to the prognosis of AIS after intravenous thrombolysis.
万方数据
维普
