Objective To analyze the relationship between CT coronary calcification score and the degree of coronary stenosis in coronary heart disease and the value of predicting cardiovascular adverse events(MACE).Methods A total of 108 patients with coronary heart disease admitted to our hospital from July 2020 to July 2021 were selected as the study objects.All patients received coronary CT angiography(CTA)examination,computed CT coronary artery calcification scores,and analyzed the relationship between CT coronary artery calcification scores(TCS and Shemesh scores)and coronary artery stenosis degree.General data(gender,age,underlying diseases,smoking history,etc.)of all patients were collected and divided into MACE group and non-MACE group according to whether they were combined with MACE.The risk factors of MACE were analyzed by univariate and multivariate Logistic regression.ROC curve was drawn to analyze the value of CT coronary calcification score in predicting the occurrence of MACE.Results According to the results of coronary angiography,108 patients with CHD were divided into mild stenosis group 43 cases(39.81％),moderate stenosis group 51 cases(47.22％),and severe stenosis group 14 cases(12.96％).TCS score and Shemesh score were the highest in severe stenosis group,followed by moderate stenosis group,and the lowest in mild stenosis group(P＜0.05).Kendall's tau-b(K)test showed that TCS score and Shemesh score were positively correlated with the degree of coronary artery stenosis(r=0.751,0.674,P＜0.05).Pearson correlation showed that TCS score of CHD patients was positively correlated with Shemesh score(r=0637,P＜0.05).There was no significant difference in gender,age,BMI,course of disease,smoking history,diabetes,hypertension and dyslipidemia between MACE group and non-MACE group(P＞0.05).The scores of NT-proBNP,TCS and Shemesh in MACE group were higher than those in non-MACE group(P＜0.05).Logistic regression analysis showed that NT-proBNP,TCS score and Shemesh score were the risk factors for coronary heart disease combined with MACE(OR＞1,P＜0.05).ROC curve results show that,The AUC of TCS score,Shemesh score and combined prediction of coronary heart disease with MACE were 0.796(95％CI:0.694-0.899),0.770(95％CI:0.648-0.891),0.816(95％CI:0.722-0.909).Conclusion CT coronary artery calcification score is positively correlated with the degree of coronary artery stenosis in CHD.TCS score and Shemesh score are risk factors affecting the occurrence of MACE,and their combination can improve the value of predicting the occurrence of CHD with MACE.
关键词
冠心病/冠脉狭窄程度/CT冠脉钙化积分/心血管不良事件/预测价值
Key words
Coronary Heart Disease/Degree of Coronary Artery Stenosis/CT Coronary Artery Calcification Score/Cardiovascular Adverse Events/Predictive Value
维普
万方数据