中国CT和MRI杂志2024,Vol.22Issue(10) :68-71.DOI:10.3969/j.issn.1672-5131.2024.10.022

基于CCTA衍生人工智能测量冠周FAI评估冠状动脉粥样硬化疗效的可行性研究

Feasibility Study of Assessing the Efficacy of Coronary Atherosclerosis Based on CCTA-Derived Artificial Intelligence Measurement of Pericoronary Fat Attenuation Index(Pericoronary FAI)

杨锟 王利东
中国CT和MRI杂志2024,Vol.22Issue(10) :68-71.DOI:10.3969/j.issn.1672-5131.2024.10.022

基于CCTA衍生人工智能测量冠周FAI评估冠状动脉粥样硬化疗效的可行性研究

Feasibility Study of Assessing the Efficacy of Coronary Atherosclerosis Based on CCTA-Derived Artificial Intelligence Measurement of Pericoronary Fat Attenuation Index(Pericoronary FAI)

杨锟 1王利东2
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作者信息

  • 1. 包头医学院(内蒙古包头 014040)
  • 2. 内蒙古自治区国际蒙医医院影像中心(内蒙古呼和浩特 010013)
  • 折叠

摘要

目的 本研究旨在基于CCTA衍生人工智能测量冠状动脉周围脂肪衰减指数(冠周FAI)对冠状动脉粥样硬化疗效评估,研究其能否为冠状动脉疾病(CAD)患者预后情况提供诊疗证据.方法 入选包头市中心医院2022年治疗后的CAD患者作为研究对象.按照治疗方法和疗效情况分成六组.行冠状动脉计算机断层扫描血管造影(CCTA)检查符合纳排标准.收集患者基线资料和临床指标等.由2名具有主治医师以上职称医师使用使用CT工作软件进行图像后处理,后用Skview软件FAI智能分析系统测量并记录冠周FAI.采用皮尔逊相关性分析法和秩相关分析法探究冠周FAI与指标相关性.结果 本研究CCTA图像后处理结果显示总体冠周FAI为-83.10±10.46HU,六组冠周FAI分别为-89.71±5.56HU、-71.35±4.39HU、-91.94±3.97HU、-71.62±4.79HU、-89.38±3.07HU、-71.69±3.79HU.PCI疗效效果强于药物及CABG.治疗方法和疗效情况与临床指标呈不同相关性.结论 基于CCTA衍生人工智能测量冠周FAI能够对冠状动脉粥样硬化疗效进行评估并且识别分类残余炎症风险(RIR),从而帮助临床了解CAD患者预后情况.

Abstract

Objective The aim of this study was to assess the efficacy of coronary atherosclerosis based on the CCTA-derived artificial intelligence measure of pericoronary fat attenuation index(pericoronary FAI),and to investigate whether it can provide diagnostic and therapeutic evidence of prognostic conditions of patients with coronary artery disease(CAD).Methods CAD patients treated in Baotou Central Hospital 2022 were enrolled as study subjects.They were divided into six groups according to treatment methods and efficacy.Coronary computed tomography angiography(CCTA)was performed to meet the criteria for natriuresis.Patients'baseline data and clinical indicators were collected.Two physicians with the title of attending physician or above performed image post-processing using CT work software,and then measured and recorded pericoronary FAI using the FAI intelligent analysis system of Skview software.Pearson's correlation analysis and rank correlation analysis were used to investigate the correlation between peri-coronary FAI andthe indexes.Results The post-processing results of CCTA images in this study showed that the totality pericoronary FAI was-83.10±10.46 HU,and the pericoronary FAI of the six groups were-89.71±5.56 HU,-71.35±4.39 HU,-91.94±3.97 HU,-71.62±4.79 HU,-89.38±3.07 HU,-71.69±3.79 HU.PCI efficacy results were stronger thandrug and CABG efficacy.Treatment methods and efficacy profiles showed differentcorrelations with clinical indicators.Conclusion CCTA-derived artificial intelligence-based measurement of pericoronary FAI enables assessment of coronary atherosclerosis efficacy and identification of categorized residual inflammatory risk(RIR),thus helping to provide clinical insight into the prognosis of patients with CAD.

关键词

冠状动脉疾病/冠状动脉计算机断层扫描血管造影术/冠状动脉周围脂肪衰减指数/他汀类药物/经皮冠状动脉介入术/冠状动脉旁路移植术

Key words

Coronary Artery Disease/Coronary Computed Tomography Angiography/Pericoronary Fat Attenuation Index/Statins/Percutaneous Coronary Intervention/Coronary Artery Bypass Grafting

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基金项目

2022年度自治区卫生健康科技计划项目(202201081)

出版年

2024
中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
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