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心脏磁共振成像联合超声心动图对肥厚型心肌病的诊断价值

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目的 探讨心脏磁共振(CMR)联合超声心动图(UCG)对肥厚型心肌病(HCM)的诊断价值.方法 选择2020年01月-2023年02月于邯郸市中心医院收治的80例HCM患者作为研究组,另随机选择同期体检健康者80例作为对照组.所有受试者均接受CMR和UCG检查,比较两组间CMR和UCG定量参数的差异.通过多因素Logistic回归分析,绘制受试者工作特征曲线(ROC)并计算曲线下面积(AUC)评估CMR、UCG定量参数单独和联合诊断HCM的效能.结果 研究组CMR参数[左心室射血分数(EF)、舒张末期左心室质量(LVEDM)、左心室壁最厚处厚度(MWT)、钆延迟强化(LGE)阳性比例)]、UCG参数[舒张末期左心室后壁厚度(LVPWD)、舒张末期室间隔厚度(IVSD)、MWT、二尖瓣口舒张早期血流速度与室间隔和侧壁均值的比值(E/e')、EF]均显著高于对照组(P均<0.05),而CM R参数[左心室舒张末期容积(EDV)、左心室收缩末期容积(ESV)]、UCG参数[左心室舒张末期横径(LVEDD)、二尖瓣口舒张早期血流速度与舒张晚期血流速度的比值(E/A)、EDV、ESV]均显著低于对照组(P均<0.05).通过多因素Logistic回归分析以及ROC曲线发现,与单一参数诊断相比较,CMR结合UCG定量参数对HCM诊断的AUC、约登指数、敏感度、特异度最高(P<0.05).结论 CMR结合UCG对HCM具有更高的诊断价值,对临床诊疗方式选择有一定的影像学参考依据.
Diagnostic Value of Cardiac Magnetic Resonance Imaging Combined with Echocardiographyin Patients With Hypertrophic Cardiomyopathy
Objective To explore the diagnostic value of cardiac magnetic resonance(CMR)combined with echocardiography(UCG)in hypertrophic cardiomyopathy(HCM).Methods A total of 80 HCM patients admitted to Handan Central Hospital from January 2020 to February 2023 were selected as the study group,and 80 healthy people who underwent physical examination during the same period were randomly selected as the control group.All subjects underwent CMR and UCG tests to compare the differences in CMR and UCG quantitative parameters between the two groups.Multivariate Logistic regression analysis was performed to plot receiver operating characteristic curve(ROC)and calculate area under the curve(AUC)to evaluate the efficacy of CMR and UCG quantitative parameters in the diagnosis of HCM alone and in combination.Results In the study group,CMR parameters[left ventricular ejection fraction(EF),end-diastolic left ventricular mass(LVEDM),left ventricular wall thickness at the thickest point(MWT),gadolinium-delayed reinforcement(LGE)positive ratio)],UCG parameters[end-diastolic posterior left ventricular wall thickness(LVPWD),end-diastolic septal thickness(IVSD),MWT,mitral valve oral relaxation The ratio of blood flow velocity to the mean value of interventricular septum and lateral wall(E/e')and EF]in early Zhang period were significantly higher than those in control group(P<0.05).The CMR parameters[left ventricular end-diastolic volume(EDV),left ventricular end-systolic volume(ESV)],UCG parameters[left ventricular end-diastolic transverse diameter(LVEDD),ratio of early diastolic blood flow velocity to late diastolic blood flow velocity(E/A),EDV,ESV]were significantly lower than those of control group(P<0.05).Multivariate Logistic regression analysis and ROC curve showed that compared with single parameter diagnosis,CMR combined with UCG quantitative parameters had the highest AUC,Yoden index,sensitivity and specificity for HCM diagnosis(P<0.05).Conclusion CMR combined with UCG has higher diagnostic value for HCM,and has certain imaging reference for the selection of clinical diagnosis and treatment.

EchocardiographyMagnetic Resonance ImagingHypertrophic CardiomyopathyDiagnostic Value

贾臣英、李建丽、支元、李新、任彦斌

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邯郸市中心医院超声医学科

邯郸市中心医院CT及磁共振室(河北邯郸 056001)

超声心动图 磁共振成像 肥厚型心肌病 诊断价值

河北省重点研发计划项目

21366781D

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(10)