Quantitative Measurement of Pancreatic CT Values in Predicting the Incidence of Type 2 Diabetes Mellitus and Related Factors
Objective To investigate the incidence of type 2 diabetes mellitus(T2DM)predicted by quantitative measurement of pancreatic CT value,and to explore the differences of biochemical indexes including triglyceride(TG),total cholesterol(TC),high-density lipoprotein(HDL)and low-density lipoprotein(LDL)between T2DM group and normal blood glucose group.Methods A total of 233 patients were retrospectively analyzed and the CT value of pancreas was measured,including 114 patients in type 2 diabetes group and 119 patients in normal group.The correlation between the CT value of pancreas and fasting blood glucose was analyzed.The cut-off value of fasting blood glucose was 7.0mmol/L,and the ROC curve was drawn to evaluate the diagnostic efficiency.Independent sample t test was performed to analyze the difference of pancreatic CT value,triglyceride(TG),total cholesterol(TC),high density lipoprotein(HDL)and low density lipoprotein(LDL)between type 2 diabetes group and normal group.Results The correlation coefficient between pancreatic CT value and fasting blood glucose was-0.465(P＜0.001).When fasting blood glucose was 7.0mmol/L as the cut-off value,the cut-off value of ROC curve analysis for predicting abnormal blood glucose was 39HU,AUC was 0.839,sensitivity was 70.2％,specificity was 84.0％,and Youden index was 0.542.There were significant differences in pancreatic CT value and triglyceride(TG)between T2DM group and normal group(P＜0.05),but no significant differences in total cholesterol(TC),high density lipoprotein(HDL)and low density lipoprotein(LDL)(P＞0.05).Conclusion Pancreatic CT value reflects the degree of pancreatic fatty infiltration,which is positively correlated with triglyceride(TG).The quantitative measurement of pancreatic CT value can be used to predict the occurrence of type 2 diabetes mellitus.
万方数据
维普
