MRI Study on Correlation between Size and Signal Intensity of IPFP and Patellofemoral Joint Structural Damage
Objective To investigate the associations between size and signal intensity of Infrapatellar fat pad(IPFP)and patellofemoral joint structural damage.Methods The clinical and imaging data of 100 subjects who both underwent knee of X-ray and MRI were retrospectively collected and analyzed.The thickness and maximum cross-sectional area(CSA)of IPFP were measured on sagittal PDWI-FS sequence images,and the signal intensity of IPFP were evaluated semiquantitatively.MRI was used to assess patellar cartilage defects,osteophytes and bone marrow lesions,and their correlations with the IPFP size and signal intensity were analyzed.According to the K-L classification on X-ray films,the participants were further divided into ROA and non-ROA group to compare the differences of IPFP between them.Results The thickness and maximum CSA of IPFP were negatively correlated with patellar cartilages and osteophytes(P<0.05),the signal intensity of IPFP was positively associated with patellar cartilages and osteophytes(P<0.05).IPFP thickness and maximum CSA were smaller in the ROA group compared to the non-ROA group,IPFP signal intensity was higher in the ROA group compared to the non-ROA group,and the differences were statistically significant(P<0.05).Conclusion IPFP size and increased signal are associated with patellofemoral joint structural damage,suggesting that IPFP may be the potential influencing factors for the development and progression of patellofemoral joint osteoarthritis.