Multimodal Imaging Method for Evaluating the Therapeutic Effect of Buyi Medicine Deer Antler and Bone Strengthening Decoction on Fractures
Objective Using multimodal imaging methods to evaluate the therapeutic effect of Buyi medicine deer antler bone strengthening decoction on fractures.Methods 30 New Zealand white rabbits with left lower limb tibia fracture models were made through surgery.They were randomly divided into an experimental group of 15 rabbits and treated with Buyi medicine deer antler and strong bone decoction by gavage,while the control group of 15 rabbits was treated with an equal amount of 0.9％physiological saline by gavage.On the day of modeling,7d,15d,21d,30d,and 42d after modeling,two model rabbits were randomly selected to undergo conventional DR imaging,conventional CT,and dual energy CT scans,respectively.The CT scan data were subjected to post-processing of coronal sagittal and bone marrow imaging,and the display of fracture ends in the experimental group and control group using different imaging methods was compared.Results Compared with the control group,the experimental group showed statistical differences in X-ray,CT plain scan,and dual energy bone marrow imaging evaluations(P＞0.05),and the combination of CT plain scan and dual energy bone marrow imaging was more sensitive and accurate in evaluating fracture healing;For the comparison of fracture healing cycles,the experimental group had a significantly shorter healing cycle compared to the control group,and the repair score of the fracture at the 7-day time point increased by 97.3％compared to the control group.Conclusion Buyi medicine deer antler bone strengthening decoction can promote callus growth,shorten the course of fracture,and CT plain scan combined with dual energy bone marrow imaging is more sensitive and accurate in evaluating fracture healing.
Dual Source CTFractureBuyi Medicine Deer Antler Bone Strengthening DecoctionImage Multimodality
万方数据
维普
