Objective To evaluate the value of whole body diffusion weighted imaging(WB-DWI)in the detection of active lesions in patients with Ankylosing spondylitis(AS).Methods Retrospective analysis was made on 181 patients with Ankylosing spondylitis who were admitted to the Rheumatology and Immunology Department of the First Affiliated Hospital of Nanjing Medical University from June 2019 to August 2022.In addition to the routine scanning MRI scheme,all patients underwent the same whole body MRI scanning scheme.The scanning sequences mainly included the whole body coronal short-term inversion recovery sequence(STIR)and the whole body diffusion weighted imaging sequence(WB-DWI).Two doctors with the professional title of deputy high or above independently analyzed the coronal STIR sequence image and the coronal DWI sequence inversion image,and diagnosed and analyzed whether the specific joint anatomical area was involved(the involvement was mainly manifested as the high signal area on the STIR image and the low signal area with limited diffusion on the DWI inversion image).The evaluation sites mainly included the cervical vertebra,thoracic vertebra,lumbar vertebra,sternum,Shoulder joint,acromioclavicular joint,sternoclavicular joint,hip joint,ischia The pubic bone and sacroiliac joint were involved,and the number of lesions detected in each region was calculated.Mann Whitney test was used to analyze the detection of lesions in different anatomical regions using two sequences.Results Out of all 181 AS patients,129 patients detected active lesions in different anatomical regions mentioned above,with the highest detection rate being in the thoracic spine(526 detected on WB-DWI and 384 detected on STIR),followed by the lumbar spine(183 detected on WB-DWI and 115 detected on STIR),and the least number of lesions detected on the sitting bone(10 detected on WB-DWI and 7 detected on STIR).The WB-DWI sequence showed statistically significant differences in the number of lesions detected in the thoracic spine,sternum,and sternoclavicular joint compared to the STIR sequence.Conclusion WB-DWI has certain advantages over the whole body coronal STIR sequence in the detection of systemic active lesions in patients with Ankylosing spondylitis,and it is a better alternative sequence.
关键词
强直性脊柱炎/活动性病灶/全身磁共振成像/全身弥散加权序列
Key words
Ankylosing Spondylitis/Active Lesions/Whole Body Magnetic Resonance Imaging/Whole Body Diffusion Weighted Sequence
维普
万方数据