MRI Diagnosis of Type 2 Diabetic Foot with Osteomyelitis and Its Influencing Factors
Objective To investigate the magnetic resonance imaging(MRI)features of type 2 diabetic foot with osteomyelitis(DFO)and its influencing factors.Methods The clinical data of 200 patients with type 2 diabetic foot admitted to the hospital from September 2022 to September 2023 were analyzed retrospectively.According to the presence or absence of osteomyelitis,the patients were divided into observation group(86 patients with osteomyelitis)and control group(114 patients without osteomyelitis).All patients received MRI examination and their MRI signs were analyzed.Logistic regression analysis was conducted to identify the influencing factors of DFO.Results Gram negative bacteria were main pathogenic bacteria of DFO.The main MRI features included low signal on T1WI and high signal on T2WI with obvious enhancement.Comparison of MRI quantitative parameters found that the percentage of contrast agent in extracellular space,volume transfer constant and rate constant in the observation group were higher than those in the control group(P<0.05).There was no statistically significant difference between the two groups in terms of gender,age,duration of type 2 diabetes,smoking history,diabetic nephropathy,HDL-C,LDL-C,HbAlc,PCT,Scr and FBG(P>0.05).There were statistically significant differences in the duration of diabetic foot,ulcer area,multi-drug resistant bacterial infection and CRP(P<0.05).Logistic regression analysis found that the duration of diabetic foot>2 months,ulcer area>4 cm2,multiple drug-resistant bacterial infections and high CRP level were influencing factors of DFO.Conclusion MRI images of patients with DFO show low signal on T1WI and high signal on T2WI,accompanied by significant enhancement.At the same time,MRI quantitative parameters are significantly increased,which is important for clinical diagnosis of the disease.In addition,patients with long course of diabetic foot,large ulcer area,multi-drug resistant bacterial infections and high CRP level should be alert to the occurrence of osteomyelitis.
Type 2 Diabetic FootOsteomyelitisMRIInfluencing Factor