首页|2型糖尿病足合并骨髓炎的MRI诊断及其影响因素分析

2型糖尿病足合并骨髓炎的MRI诊断及其影响因素分析

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目的 探讨2型糖尿病足合并骨髓炎(DFO)的磁共振(MRI)诊断及其影响因素分析.方法 回顾性分析2022年9月至2023年9月我院收治的200例2型糖尿病足患者临床资料,依据是否合并骨髓炎分成观察组(合并骨髓炎)86例与对照组(未合并骨髓炎)114例.所有患者均行MRI检查,并分析两组MRI征象.收集所有患者临床资料,运用Logistic回归分析得到DFO的影响因素.结果 DFO病原菌分布以革兰阴性菌为主,MRI图像特征以低T1WI信号、等高T2WI信号伴明显强化为主.比较两组MRI定量参数,可见观察组细胞外液间隙对比剂百分比、容积转移常数及速率常数均高于对照组,差异有统计学意义(P<0.05).两组性别、年龄、2型糖尿病病程、吸烟史、糖尿病肾病、HDL-C、LDL-C、HbAlc、PCT、Scr及FBG比较差异不具有统计学意义(P>0.05),糖尿病足病程、溃疡面积、多重耐药菌感染及CRP比较差异有统计学意义(P<0.05),进一步行Logistic回归分析,结果显示糖尿病足病程≥2个月、溃疡面积≥4cm2、多重耐药菌感染及高水平CRP为DFO影响因素.结论 DFO表现为T1WI低信号,T2WI高信号,且伴明显强化,同时MRI定量参数水平明显升高,对于临床判断疾病具有重要价值.此外,对于糖尿病足病程长、溃疡面积大、多重耐药菌感染及CRP水平高的患者应警惕骨髓炎的出现.
MRI Diagnosis of Type 2 Diabetic Foot with Osteomyelitis and Its Influencing Factors
Objective To investigate the magnetic resonance imaging(MRI)features of type 2 diabetic foot with osteomyelitis(DFO)and its influencing factors.Methods The clinical data of 200 patients with type 2 diabetic foot admitted to the hospital from September 2022 to September 2023 were analyzed retrospectively.According to the presence or absence of osteomyelitis,the patients were divided into observation group(86 patients with osteomyelitis)and control group(114 patients without osteomyelitis).All patients received MRI examination and their MRI signs were analyzed.Logistic regression analysis was conducted to identify the influencing factors of DFO.Results Gram negative bacteria were main pathogenic bacteria of DFO.The main MRI features included low signal on T1WI and high signal on T2WI with obvious enhancement.Comparison of MRI quantitative parameters found that the percentage of contrast agent in extracellular space,volume transfer constant and rate constant in the observation group were higher than those in the control group(P<0.05).There was no statistically significant difference between the two groups in terms of gender,age,duration of type 2 diabetes,smoking history,diabetic nephropathy,HDL-C,LDL-C,HbAlc,PCT,Scr and FBG(P>0.05).There were statistically significant differences in the duration of diabetic foot,ulcer area,multi-drug resistant bacterial infection and CRP(P<0.05).Logistic regression analysis found that the duration of diabetic foot>2 months,ulcer area>4 cm2,multiple drug-resistant bacterial infections and high CRP level were influencing factors of DFO.Conclusion MRI images of patients with DFO show low signal on T1WI and high signal on T2WI,accompanied by significant enhancement.At the same time,MRI quantitative parameters are significantly increased,which is important for clinical diagnosis of the disease.In addition,patients with long course of diabetic foot,large ulcer area,multi-drug resistant bacterial infections and high CRP level should be alert to the occurrence of osteomyelitis.

Type 2 Diabetic FootOsteomyelitisMRIInfluencing Factor

吴琼、吴海燕、朱莉莉

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中国人民解放军东部战区空军医院医学影像科(江苏南京 210002)

2型糖尿病足 骨髓炎 MRI 影响因素

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(10)