Diagnostic Value and Clinical Application of MRI in Patients with Gliomas of Varying Malignancy
Objective To investigate the diagnostic value and clinical application of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in gliomas of varying malignancy.Methods A total of 80 glioma patients,treated between January 2019 and January 2024,were enrolled in this study.All patients underwent pathological examination and DCE-MRI.Based on the degree of malignancy,patients were divided into low-grade(n=24)and high-grade(n=56)groups,and their predictive value and correlations were analyzed.Results The low-grade group exhibited higher Ktrans,Ve,and MVD values,while ADC values were lower compared to the high-grade group(P＜0.05).DCE-MRI demonstrated high sensitivity(95.83％)and specificity(92.86％)in diagnosing the malignancy of gliomas.ROC curve analysis revealed that the ROC values for Ktrans,Ve,ADC,and MVD were 0.747,0.810,0.687,and 0.664,respectively(P＜0.05).Correlation analysis indicated a positive correlation between Ktrans,Ve,and MVD(r=0.527,P＜0.001),and a negative correlation between ADC and MVD(r=-0.563,P＜0.001).Conclusion DCE-MRI holds significant diagnostic value in assessing gliomas of different malignancy levels,with relevant parameters closely correlated with microvascular density and the degree of malignancy,thus providing critical insights for the diagnosis and prognosis of gliomas.
GliomaMalignancyDCE-MRIImaging CharacteristicsDiagnostic Value
万方数据
维普
