Diagnostic Efficiency of MSCT Combined with CEA and CA724 in Lung Cancer
Objective To explore the diagnostic efficiency of multi-slice spiral computed tomography(MSCT)combined with carcinoembryonic antigen(CEA)and carbohydrate antigen 724(CA724)in lung cancer.Methods A retrospective analysis was performed on diagnosis and treatment data of 60 patients with lung lesions in the hospital between January 2021 and December 2023.All patients underwent pathological examination,MSCT examination,serum CEA and CA724 detection.Taking pathological results as the golden standard,diagnostic efficiency of MSCT,CEA,CA724 and combined detection was analyzed.Results The pathological diagnosis showed that there were 37 cases(61.67％)with lung cancer and 23 cases(38.33％)with benign lesions.The levels of serum CEA and CA724 in lung cancer group were higher than those in benign group(P＜0.05).Kappa value between combined detection(MSCT,CEA and CA724)and pathological examination in the diagnosis of lung cancer was 0.929(P＜0.05),greater than that of MSCT CEA,CA724 and CEA+CA724(0.685,0.553,0.450,0.615;P＜0.05).Taking pathological results as the golden standard,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of MSCT combined with CEA and CA724 in the diagnosis of lung cancer were all＞90％,higher than those of single index.Conclusion MSCT combined with CEA and CA724 can effectively improve diagnostic efficiency in lung cancer,with high clinical application value.
万方数据
维普
