Imaging Characteristics of MR HASTE and Construction of Diagnostic Model in Patients with Benign and Malignant Masses of Mediastinum and Hilus Pulmonis
Objective To explore imaging characteristics of magnetic resonance(MR)half-Fourier acquisition single-shot turbo spin-echo(HASTE)and construct the relevant diagnostic model in patients with benign and malignant masses of mediastinum and hilus pulmonis.Methods A total of 102 patients with masses of mediastinum and hilus pulmonis in the hospital were enrolled between October 2021 and May 2023.According to random number table method,they were divided into training set(72 cases)and test set(30 cases).All patients underwent MR HASTE,enhanced CT scan and pathological examination.The results of pathological diagnosis were compared between training set and test set.Imaging characteristics of MR HASTE in patients with benign and malignant masses of mediastinum and hilus pulmonis were analyzed.Taking pathological diagnosis as the golden standard,the consistency between different methods and pathological examination in the diagnosis of mediastinum and hilus pulmonis masses was analyzed.MR HASTE model,MSCT enhanced model and MR HASTE+MSCT enhanced model were constructed,and their diagnostic efficiency for malignant masses was evaluated by receiver operating characteristic(ROC)curves.The differences in diagnostic efficiency of different models were evaluated by Delong test.The fit of the combined model was detected by Hosmer-Lemeshow.Results Pathological examination showed that in training set,there were 62 cases with malignant lesions and 10 cases with benign masses.In test set,there were 24 cases with malignant lesions and 6 cases with benign lesions.Imaging characteristics of MR HASTE in benign masses were as follows:regular lesion morphology,clear boundary,even signals in lesions,no peripheral metastasis,more dark and less brightness in T2WI images.Imaging characteristics of MR HASTE in malignant masses were as follows:irregular lesion morphology,unclear boundary,uneven and high,equal or low mixed signals in lesions,spot-like and strip-like high signals in lesions.In training set,sensitivity and Kappa values of MR HASTE,MSCT enhancement and MR HASTE+MSCT enhancement in the diagnosis of benign and malignant masses were(87.10％,91.94％,96.77％)and(0.536,0.498,0.768),respectively.ROC curves,DeLong test and Hosmer-Lemeshow test showed that in test set,AUC of combined model in the diagnosis of malignant masses was better than that of MR HASTE model and MSCT enhanced model alone(P＜0.05).Conclusion Imaging characteristics of MR HASTE in benign masses of mediastinum and hilus pulmonis are as follows:regular lesion morphology,clear boundary,even signals in lesions,no peripheral metastasis.Imaging characteristics of MR HASTE in malignant masses are as follows:irregular lesion morphology,unclear boundary,uneven and mixed signals in lesions,spot-like high signals in lesions.MR HASTE+MSCT enhanced model has the highest diagnostic efficiency for benign and malignant masses.
MediastinumHilus PulmonisMassBenign and MalignantMagnetic ResonanceHalf-fourier Acquisition Single-shot Turbo Spin-echoImaging CharacteristicDiagnostic Model
万方数据
维普
