Value of Multimodal MRI in the Differential Diagnosis of BI-RADS 4 Breast Nodules
Objective To explore the value of multimodal magnetic resonance imaging(MRI)in the differential diagnosis of breast imaging reporting and data system(BI-RADS)4 breast nodules.Methods A retrospective analysis was performed on the clinical data of 83 patients who were confirmed with BI-RADS 4 breast nodules by routine ultrasound in the hospital between April 2021 and April 2024.All patients underwent routine MRI,diffusion-weighted imaging(DWI),dynamic contrast-enhanced MRI(DCE-MRI)and pathological examinations.Taking pathological results as the golden standard,the value of different MRI methods in the differential diagnosis of benign and malignant BI-RADS 4 breast nodules was analyzed.Results The pathological results showed that in the in 83 patients,there were 44 cases(53.01％)with benign nodules(benign group)and 39 cases(46.99％)with malignant nodules(malignant group).There were significant differences in multimodal MRI findings[lesion morphology,edge features,enhancement modes,internal necrosis and cystic lesion area,maximum intensity projection(MIP)]between the two groups(P＜0.05).The proportion of type Ⅲ time-signal intensity curve(TIC)in malignant group was higher than that in benign group,while apparent diffusion coefficient(ADC),proportions of type Ⅰ and Ⅱ TIC were lower than those in benign group(P＜0.05).Taking pathological results as the golden standard,Kappa values of DWI and DCE-MRI in the differential diagnosis of benign and malignant BI-RADS 4 breast nodules were 0.518 and 0.638(P＜0.05),lower than that of combined multimodal MRI(0.855,P＜0.05).The diagnostic sensitivity,specificity and accuracy of combined multimodal MRI were higher than those of single detection.Conclusion Multimodal MRI can clearly display different lesion morphology,enhancement modes,blood flow distribution and cells metabolism level in benign and malignant BI-RADS 4 breast nodules,which has certain differential diagnosis value for properties of breast nodules.
Breast NoduleBI-RADS 4Multimodal Magnetic Resonance ImagingDiffusion-weighted ImagingDynamic Contrast-enhanced ScanDifferential Diagnosis
万方数据
维普
