Study on the Degrading Value Of MRI for Suspicious Breast Lesions Detected by Ultrasound
Objective This study was to investigate the value of breast MRI in the degradation of suspicious lesions classified as BI-RADS 4A and 4B.Methods Patients who underwent breast MRI with suspicious lesions classified as 4A and 4B were included in this review study,and MR Images were evaluated by two specialists.On the basis of dynamic enhanced MRI(DCE-MRI)and diffusion-weighted imaging(DWI),the classification of MRI BI-RADS is given by consensus.Pathological findings and imaging follow-up for at least 12 months were used as reference standards.Sensitivity,specificity,positive predictive value(PPV),NPV and 95％confidence interval(CI)were calculated.Results 167 patients with 186 lesions(US 4A:145,US 4B:41)comprised the study cohort,with a cancer rate of 34.9％(65/186).MRI showed true positives for all malignancies,and 92.6％(112/121)of benign lesions were correctly diagnosed.MRI increased PPV from 34.9％(65/186)to 87.8％(65/74),and reduced the false positive rate by 92.6％(112/121).MRI of the sensitivity,specificity,PPV and NPV of 100％(95％CI:94.5％～100％),92.6％(95％CI:86.3％～96.5％),87.8％(95％CI:78.2％～94.3％)and 100％(95％CI:96.8％～100％).2.2％(4/186)of the suspected lesions were detected on MRI,of which 75％(3/4)were malignant lesions.Conclusion MRI can reduce the grade of suspected lesions of BI-RADS 4A and 4B,avoid unnecessary benign biopsy,and will not miss malignant lesions.Other suspicious lesions found on the MRI require further examination.
万方数据
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