MSCT Imaging Features and Prognostic Risk Factors of Spontaneous Rupture Hemorrhage in Elderly Hepatocellular Carcinoma
Objective To analyze the multilayer spiral computed tomography(MSCT)imaging features of spontaneous rupture hemorrhage(SRHC)in elderly patients with hepatocellular carcinoma and to analyze the risk factors affecting the prognosis of patients with SRHC.Methods The clinical data of 42 elderly patients with SRHC admitted to our hospital from March 2018 to February 2021(bleeding group)and 84 patients with hepatocellular carcinoma without spontaneous bleeding(non-bleeding group)matched for age and gender and other baseline information during the same period were reviewed.The MSCT imaging features of patients in the two groups were compared.The prognosis and survival of patients in the bleeding group and the non-bleeding group were followed up and counted.Cox proportional hazard regression was used to analyze the factors influencing the overall survival of elderly patients with liver cancer.Results The proportion of patients with alpha-fetoprotein(AFP)＞400μg/L and liver function grade B was higher in the bleeding group than in the non-bleeding group(P＜0.05).The proportion of patients with maximum tumour diameter ≥10cm,tumour distribution across lobes,bowstring ratio＞1,diaphragmatic invasion,cirrhosis,tumour ectasia accounting for≥25％,and patients with portal vein obstruction were higher in the bleeding group than in the non-bleeding group(P＜0.05).The mean survival time for patients in the bleeding versus non-bleeding group was(16.48±2.04)months and(25.06±1.39)months.The overall survival rates of patients in the bleeding and non-bleeding groups at 1 year and 3 years were 71.4％,20.4％and 85.7％,46.2％,respectively.Kaplan-Meier survival analysis showed a statistically significant difference in cumulative survival between the bleeding and non-bleeding groups(Log Rank x2=12.822,P＜0.001).Conclusion Multiple imaging features of MSCT are closely associated with the development of spontaneous rupture haemorrhage in elderly patients with liver cancer,and spontaneous rupture haemorrhage is an independent risk factor for overall survival in elderly patients with liver cancer.
万方数据
维普
