Evaluation Value of Abdominal Fat Distribution Based on CT Assessment for the Severity and Prognosis of Acute Pancreatitis
Objective To explore the evaluation value of abdominal fat distribution based on CT assessment for the severity and prognosis of acute pancreatitis.Methods The clinical data were collected from 80 patients with severe acute pancreatitis(SAP group)treated in the hospital between January 2020 and February 2023,and 42 patients with mild acute pancreatitis(MAP)during the same period were enrolled as MAP group.The clinical data and abdominal fat distribution parameters[visceral adipose tissue(VAT)area,subcutaneous adipose tissue(SAT)area,total fat(TAT)area,VAT/TAT ratio,VAT/SAT ratio]were compared between SAP group and MAP group.The evaluation value of abdominal fat distribution based on CT assessment for the severity and acute pancreatitis was analyzed by receiver operating characteristic(ROC)curves.According to prognosis,SAP patients were further divided into survival(n=62)and death(n=18).The evaluation value of abdominal fat distribution based on CT assessment for the prognosis of acute pancreatitis was analyzed.Results There was no significant difference in gender,age,smoking history,drinking history,hypertension history,history of diabetes mellitus,hyperlipidemia history or history of bile duct diseases between SAP group and MAP group(P＞0.05),there were significant differences in BMI,CTSI and EPIC scores(P＜0.05),and there was no significant difference in SAT area(P＞0.05).VAT area,TAT area,VAT/TAT and VAT/SAT in SAP group were higher than those in MAP group(P＜0.05).ROC curves analysis showed that area under the curve(AUC)values of VAT area,TAT area,VAT/TAT and VAT/SAT for evaluating the severity of acute pancreatitis were 0.838,0.755,0.701 and 0.853,all showing certain diagnostic value.There was no significant difference in SAT area,VAT/TAT or VAT/SAT between survival group and death group(P＞0.05).VAT area and TAT area in death group were larger than those in survival group(P＜0.05).AUC values of VAT area and TAT area for evaluating the prognosis of acute pancreatitis were 0.758 and 0.673,all showing certain diagnostic value.Conclusion Abdominal fat distribution based on CT assessment has certain clinical value in evaluating the severity and prognosis of acute pancreatitis,which can be considered as reference indexes for the auxiliary diagnosis of acute pancreatitis severity and prognosis evaluation.
CTAbdominal Fat DistributionAcute PancreatitisSeverityPrognostic Value
万方数据
维普
