Clinical Features and CT/MRI Imaging of Primary Adrenocortical Carcinoma
Objective To investigate the clinical features and CT/MRI imaging findings of primary adrenocortical carcinoma(ACC).Methods The clinical datas and imaging findings of 14 patients with ACC who confirmed by surgical pathology were retrospectively analyzed,12 patients and 5 patients underwent CT and MRI plain scan with enhanced imaging,respectively.Results All 14 patients had solitary tumor(there were 4 cases on the right and 10 cases on the left);male∶female=5∶2,aged from 13 to 73 years old,5 cases were smoking,2 cases had oedema in the face and both lower limbs,7 cases were distension,abdominal pain or low back pain,1 case was dizziness with general fatigue,1 case was amenorrhea,3 cases were accidentally found by physical examination.The maximum diameter of the tumor ranged from 8.2 to 20.8 cm,among them 12 cases had irregular morphology,and 7 cases had unclear boundaries.CT(12 cases):Among 12 patients,there were 12 patients with cystic degeneration and necrosis,8 patients with calcification,and 4 patients with hemorrhage in the tumor,8 patients with thickened perirenal fascia,and the plain CT value of the solid part was(38.7±6.7)Hu.CT enhanced scan showed a larger vascular shadow in the solid part of the arterial stage,the venous stage was further enhanced than the arterial stage,the scope of enhancement was slightly expanded,and the enhancement was slightly weakened in the delayed stage;no definite enhancement was found in the cystic necrosis area in the center of the tumor.MRI(5 cases):T1WI mainly showed slightly low signal,T2WI showed mixed slightly high signal mainly,1 case of DWI had limited diffusion,there were 5 cases with intratumoral cystic necrosis and hemorrhage(including hemosiderin deposition 1 case),2 cases of scar tissue,and 1 case of lipid components.The enhancement method of enhanced scanning was similar to that of CT.There were 7 cases of delayed enhancement of tumor margin line-like capsular structure.Among the 14 patients with ACC,3 cases were associated with left renal vein tumor thrombus,and 1 case was associated with liver metastases.Conclusion The clinical symptoms of ACC are non-specific,ACC has certain imaging characteristics.CT and MRI examinations have their own advantages in the diagnosis of ACC,and the combined application is of great significance for the diagnosis and differential diagnosis of ACC.
Adrenocortical CarcinomaCTMRIEnhanced ScanningClinical Features