Objective To systematically evaluate the effect of health education intervention on endemic fluoro-sis in China from January 2000 to May 2022.Methods CNKI,VIP,CBM,Wanfang Data databases,Web of Sci-ence,PubMed and Cochrane Library databases were searched by computer to collect self before and after con-trol studies or intervention control studies on the effect of health education on endemic fluorosis.The retrieval time limit was from the establishment of the database to May 30,2022.Two researchers independently read and screened the literature,extracted relevant data,and evaluated the bias risk of the included literature.Then,revman 5.4.1 software was used for meta-analysis.Results A total of 62 studies were included.Meta analysis showed that the overall awareness rate of endemic fluorosis in China increased by 32％[95％CI(35％,29％)].Subgroup analysis showed that the awareness rate of drinking water endemic fluorosis increased by 29％,that of coal-burning endemic fluorosis increased by 37％,and that of drinking tea-drinking type fluorosis increased by 30％.Students'awareness rate increased by 32％,adults'awareness rate increased by 31％,and monks'awareness rate increased by 38％.The awareness rates in East China,North China,Cen-tral China,South China,Northwest,Southwest and Northeast China increased by 28％,26％,33％,34％,32％,35％and 30％respectively.From 2007 to 2010,from 2011 to 2014,from 2015 to 2018,and from 2019 to May 2022,it increased by 38％,31％,29％and 35％respectively.Before the intervention,the awareness rate of[20％,30％)and[30％,40％)increased the most,53％[95％CI(79％,27％)]and 54％[95％CI(59％,48％)]respectively.Conclusion Health education can effectively improve the awareness rate of endemic fluo-rosis,and health education plays a positive role in the prevention and treatment of endemic fluorosis.
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