Objective To grasp the iodine nutritional status and the disease trend of key populations in Zoucheng City after achieving the elimination of iodine deficiency disorders,so as to provide scientific basis for timely adoption of targeted prevention and reasonable iodine supplementation.Methods According to the requirements of"National Iodine Deficiency Disorders Surveillance Program"(2016 edition),the sampling areas were divided into east,west,south,north and middle regions within a city,and one town/street was selected from each region,one primary school was selected in each town/street,and 40 non-boarding students aged 8 to 10 years were selected in each primary school;at the same time,20 pregnant women were selected in each town/street.Salt samples and random urine samples were collected from students and pregnant women to test the content of salt iodine and urinary iodine.Thyroid volume of students was determined by B-ultrasound,and the rate of goiter was calculated.Results From 2018 to 2023,a total of 1 803 salt samples were tested,and 1 650 were qualified iodized salts,the average levels of salt iodine was 23.02 mg/kg,the consumption rate of qualified iodized salt was 91.51%(1 650/1 803).There were statistically significant difference in the consumption rate of qualified iodized salt among different years(x2=15.03,P<0.05).Totally 1 203 urine samples of school-age children aged 8 to 10 years were tested,and the median of urinary iodine was 155.89 μg/L;600 urine samples of pregnant women were tested,and the median of urinary iodine was 177.98 µg/L.A total of 1 203 school-age children aged 8 to 10 years were examined,and 6 with goiter.And the goiter rate was 0.5%(6/1 203).Conclusion The iodine nutrition level of the key populations in Zoucheng City is appropriate.It should continue to strengthen monitoring and timely grasp the changes in iodine nutrition levels of the key populations,and intervention of iodine deficiency disorders in key populations still needs to be improved.