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猪流感病毒的演化

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猪流感病毒(swine influenza virus,SIV)是感染猪的一种呼吸道病毒,可对公共卫生产生重要影响.以往研究通过全基因组测序以及分子生物学、流行病学等多方面的手段,全面揭示了SIV的演化进程.为了更好地理解和应对SIV演化,对其演化历程进行了简要回顾,系统梳理了其分类、基本特征、演化及流行.通过对SIV演化的深入分析,发现其基因变异频率较高,不断发生基因重配和突变,推动病毒不断演化.此外,在猪群中发现了多种亚型SIV,而且不同地区的SIV演化存在显著差异,其中一些地区的SIV可能存在感染人的潜在风险.总体而言,SIV演化是一个复杂而动态的过程,其演化趋势可能对人类和动物健康构成潜在威胁.因此,加强对SIV演化的研究,提高对其监测和控制的能力,对于维护畜牧业健康发展和公共卫生安全具有极为重要的意义.
Evolution of Swine Influenza Virus
Swine influenza virus(SIV)is a kind of respiratory virus infecting pigs,posing a threat to public health.The evolution of SIV was fully revealed by previous researches through whole genome sequencing,molecular biology,epidemiology and other tools.In order to better understand and respond to the evolution,the history of the evolution was briefly reviewed,its classification,basic characteristics,evolution and prevalence were systematically sorted out.The results showed that,based on further analysis on the evolution,the virus was driven to continuously evolve with continuous gene reassortment and mutation due to high frequency of genetic variation.Besides,multiple subtypes of SIV were found in pig populations,and evolved depending on different regions,posing potential risk of infecting humans in some regions.In conclusion,the evolution of SIV was a complex and dynamic process,and its evolutionary direction might pose potential threat to human and animal health.Therefore,the development of livestock industry and public health safety should be safeguarded through strengthening researches on the evolution of SIV and improving the capacity to monitor and prevent the virus.

SIVevolutiongene recombinationgenetic mutation

赵玉仲、韩乐斌、桑浩田、刘思当、肖一红、侯衍猛

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山东农业大学动物科技学院,山东省动物生物工程与疾病防治重点实验室,山东泰安 271018

猪流感病毒 演化 基因重配 基因突变

山东省重点研发计划

2023CXGC010705

2024

中国动物检疫
中国动物卫生与流行病学中心

中国动物检疫

影响因子:0.437
ISSN:1005-944X
年,卷(期):2024.41(3)
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