Interpretation of the international society of forensic genetics(ISFG)'s recommendations for STR sequence nomenclature
STR sequence typing based on massively parallel sequencing(MPS)technology is increasingly used in forensic DNA typing,but the problem of inconsistent rules for naming STR sequences and low automation hinder data sharing and comparison between laboratories,and is not conducive to build STR databases based on sequence polymorphisms.The International Society of Forensic Genetics(ISFG)has recently published recommendations for STR sequence nomenclature,which is expected to solve this problem.This paper reviews the ISFG's journey on STR naming,interprets the main content of the recommendations,and compares it with the current relevant standards existing in the domestic judice and public security industries,with the aim of helping peers to understand and use it.
STR nomenclatureInternational society of forensic genetics(ISFG)Capillary electrophoresis(CE)Massively parallel sequencing(MPS)